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Revolutionizing Medical Microbiology: How Molecular and Genomic Approaches Are Changing Diagnostic Techniques

Molecular and genomic approaches have revolutionized medical microbiology by offering faster and more accurate diagnostic techniques for infectious diseases. Traditional methods, which include culturing microbes and biochemical testing, are time-consuming and may not detect antibiotic-resistant stra...

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Detalles Bibliográficos
Autores principales: Goyal, Poyasha A, Bankar, Nandkishor J, Mishra, Vaishnavi H, Borkar, Sonali K, Makade, Jagadish G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646819/
https://www.ncbi.nlm.nih.gov/pubmed/38022057
http://dx.doi.org/10.7759/cureus.47106
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author Goyal, Poyasha A
Bankar, Nandkishor J
Mishra, Vaishnavi H
Borkar, Sonali K
Makade, Jagadish G
author_facet Goyal, Poyasha A
Bankar, Nandkishor J
Mishra, Vaishnavi H
Borkar, Sonali K
Makade, Jagadish G
author_sort Goyal, Poyasha A
collection PubMed
description Molecular and genomic approaches have revolutionized medical microbiology by offering faster and more accurate diagnostic techniques for infectious diseases. Traditional methods, which include culturing microbes and biochemical testing, are time-consuming and may not detect antibiotic-resistant strains. In contrast, molecular and genomic methods, including polymerase chain reaction (PCR)-based techniques and whole-genome sequencing, provide rapid and precise detection of pathogens, early-stage diseases, and antibiotic-resistant strains. These approaches have advantages such as high sensitivity and specificity, the potential for targeted therapies, and personalized medicine. However, implementing molecular and genomic techniques faces challenges related to cost, equipment, expertise, and data analysis. Ethical and legal considerations regarding patient privacy and genetic data usage also arise. Nonetheless, the future of medical microbiology lies in the widespread adoption of molecular and genomic approaches, which can lead to improved patient outcomes and the identification of antibiotic-resistant strains. Continued advancements, education, and exploration of ethical implications are necessary to fully harness the potential of molecular and genomic techniques in medical microbiology.
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spelling pubmed-106468192023-10-16 Revolutionizing Medical Microbiology: How Molecular and Genomic Approaches Are Changing Diagnostic Techniques Goyal, Poyasha A Bankar, Nandkishor J Mishra, Vaishnavi H Borkar, Sonali K Makade, Jagadish G Cureus Other Molecular and genomic approaches have revolutionized medical microbiology by offering faster and more accurate diagnostic techniques for infectious diseases. Traditional methods, which include culturing microbes and biochemical testing, are time-consuming and may not detect antibiotic-resistant strains. In contrast, molecular and genomic methods, including polymerase chain reaction (PCR)-based techniques and whole-genome sequencing, provide rapid and precise detection of pathogens, early-stage diseases, and antibiotic-resistant strains. These approaches have advantages such as high sensitivity and specificity, the potential for targeted therapies, and personalized medicine. However, implementing molecular and genomic techniques faces challenges related to cost, equipment, expertise, and data analysis. Ethical and legal considerations regarding patient privacy and genetic data usage also arise. Nonetheless, the future of medical microbiology lies in the widespread adoption of molecular and genomic approaches, which can lead to improved patient outcomes and the identification of antibiotic-resistant strains. Continued advancements, education, and exploration of ethical implications are necessary to fully harness the potential of molecular and genomic techniques in medical microbiology. Cureus 2023-10-16 /pmc/articles/PMC10646819/ /pubmed/38022057 http://dx.doi.org/10.7759/cureus.47106 Text en Copyright © 2023, Goyal et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Other
Goyal, Poyasha A
Bankar, Nandkishor J
Mishra, Vaishnavi H
Borkar, Sonali K
Makade, Jagadish G
Revolutionizing Medical Microbiology: How Molecular and Genomic Approaches Are Changing Diagnostic Techniques
title Revolutionizing Medical Microbiology: How Molecular and Genomic Approaches Are Changing Diagnostic Techniques
title_full Revolutionizing Medical Microbiology: How Molecular and Genomic Approaches Are Changing Diagnostic Techniques
title_fullStr Revolutionizing Medical Microbiology: How Molecular and Genomic Approaches Are Changing Diagnostic Techniques
title_full_unstemmed Revolutionizing Medical Microbiology: How Molecular and Genomic Approaches Are Changing Diagnostic Techniques
title_short Revolutionizing Medical Microbiology: How Molecular and Genomic Approaches Are Changing Diagnostic Techniques
title_sort revolutionizing medical microbiology: how molecular and genomic approaches are changing diagnostic techniques
topic Other
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646819/
https://www.ncbi.nlm.nih.gov/pubmed/38022057
http://dx.doi.org/10.7759/cureus.47106
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