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N-Acyloxymethyl-phthalimides deliver genotoxic formaldehyde to human cells

Formaldehyde is a pollutant and human metabolite that is toxic at high concentrations. Biological studies on formaldehyde are hindered by its high reactivity and volatility, which make it challenging to deliver quantitatively to cells. Here, we describe the development and validation of a set of N-a...

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Detalles Bibliográficos
Autores principales: Emms, Vicki L., Lewis, Liam A., Beja, Lilla, Bulman, Natasha F. A., Pires, Elisabete, Muskett, Frederick W., McCullagh, James S. O., Swift, Lonnie. P., McHugh, Peter J., Hopkinson, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646869/
https://www.ncbi.nlm.nih.gov/pubmed/38020377
http://dx.doi.org/10.1039/d3sc02867d

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