Artificial intelligence (AI) molecular analysis tool assists in rapid treatment decision in lung cancer: a case report

Leptomeningeal involvement among non-small cell lung cancer (NSCLC) patients is an aggressive form of disease that requires quick and efficient treatment. In this case report, we describe a woman in her 40s with a presenting symptom of headache that ultimately was diagnosed as leptomeningeal spread...

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Autores principales: Waissengrin, Barliz, Garasimov, Alexandra, Bainhoren, Or, Merimsky, Ofer, Shamai, Sivan, Erental, Ariel, Wolf, Ido, Hershkovitz, Dov
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646899/
https://www.ncbi.nlm.nih.gov/pubmed/37463768
http://dx.doi.org/10.1136/jcp-2023-208991
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author Waissengrin, Barliz
Garasimov, Alexandra
Bainhoren, Or
Merimsky, Ofer
Shamai, Sivan
Erental, Ariel
Wolf, Ido
Hershkovitz, Dov
author_facet Waissengrin, Barliz
Garasimov, Alexandra
Bainhoren, Or
Merimsky, Ofer
Shamai, Sivan
Erental, Ariel
Wolf, Ido
Hershkovitz, Dov
author_sort Waissengrin, Barliz
collection PubMed
description Leptomeningeal involvement among non-small cell lung cancer (NSCLC) patients is an aggressive form of disease that requires quick and efficient treatment. In this case report, we describe a woman in her 40s with a presenting symptom of headache that ultimately was diagnosed as leptomeningeal spread from NSCLC adenocarcinoma. We identified EGFR mutation in less than 48 hours from the biopsy using imagene-artificial intelligence’s real-time algorithmic solution on the pathological diagnostic slide.
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spelling pubmed-106468992023-11-15 Artificial intelligence (AI) molecular analysis tool assists in rapid treatment decision in lung cancer: a case report Waissengrin, Barliz Garasimov, Alexandra Bainhoren, Or Merimsky, Ofer Shamai, Sivan Erental, Ariel Wolf, Ido Hershkovitz, Dov J Clin Pathol Short Report Leptomeningeal involvement among non-small cell lung cancer (NSCLC) patients is an aggressive form of disease that requires quick and efficient treatment. In this case report, we describe a woman in her 40s with a presenting symptom of headache that ultimately was diagnosed as leptomeningeal spread from NSCLC adenocarcinoma. We identified EGFR mutation in less than 48 hours from the biopsy using imagene-artificial intelligence’s real-time algorithmic solution on the pathological diagnostic slide. BMJ Publishing Group 2023-11 2023-07-18 /pmc/articles/PMC10646899/ /pubmed/37463768 http://dx.doi.org/10.1136/jcp-2023-208991 Text en © Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Short Report
Waissengrin, Barliz
Garasimov, Alexandra
Bainhoren, Or
Merimsky, Ofer
Shamai, Sivan
Erental, Ariel
Wolf, Ido
Hershkovitz, Dov
Artificial intelligence (AI) molecular analysis tool assists in rapid treatment decision in lung cancer: a case report
title Artificial intelligence (AI) molecular analysis tool assists in rapid treatment decision in lung cancer: a case report
title_full Artificial intelligence (AI) molecular analysis tool assists in rapid treatment decision in lung cancer: a case report
title_fullStr Artificial intelligence (AI) molecular analysis tool assists in rapid treatment decision in lung cancer: a case report
title_full_unstemmed Artificial intelligence (AI) molecular analysis tool assists in rapid treatment decision in lung cancer: a case report
title_short Artificial intelligence (AI) molecular analysis tool assists in rapid treatment decision in lung cancer: a case report
title_sort artificial intelligence (ai) molecular analysis tool assists in rapid treatment decision in lung cancer: a case report
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646899/
https://www.ncbi.nlm.nih.gov/pubmed/37463768
http://dx.doi.org/10.1136/jcp-2023-208991
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