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Prime-boost-type PspA3 + 2 mucosal vaccine protects cynomolgus macaques from intratracheal challenge with pneumococci

BACKGROUND: Although vaccination is recommended for protection against invasive pneumococcal disease, the frequency of pneumococcal pneumonia is still high worldwide. In fact, no vaccines are effective for all pneumococcal serotypes. Fusion pneumococcal surface protein A (PspA) has been shown to ind...

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Detalles Bibliográficos
Autores principales:	Yokota, Chieko, Fujimoto, Kosuke, Yamakawa, Natsuko, Kono, Masamitsu, Miyaoka, Daichi, Shimohigoshi, Masaki, Uematsu, Miho, Watanabe, Miki, Kamei, Yukari, Sugimoto, Akira, Kawasaki, Natsuko, Yabuno, Takato, Okamura, Tomotaka, Kuroda, Eisuke, Hamaguchi, Shigeto, Sato, Shintaro, Hotomi, Muneki, Akeda, Yukihiro, Ishii, Ken J., Yasutomi, Yasuhiro, Sunami, Kishiko, Uematsu, Satoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647109/ https://www.ncbi.nlm.nih.gov/pubmed/37964391 http://dx.doi.org/10.1186/s41232-023-00305-2

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