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Diffuse Cardiac Uptake Misdiagnosed as Cardiac Amyloidosis in Bone Scan
In this presented case, a 77-year-old woman with an implanted prosthesis and ongoing knee pain underwent a bone scan using (99m)Tc-hydroxydiphosphonate (HDP) in suspicion for bone infection. An incidental finding from this scan revealed diffuse cardiac uptake, necessitating further diagnostic proced...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647204/ https://www.ncbi.nlm.nih.gov/pubmed/37958238 http://dx.doi.org/10.3390/diagnostics13213342 |
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author | Lee, Yeongjoo Jang, Jaehyuk Na, Sae Jung |
author_facet | Lee, Yeongjoo Jang, Jaehyuk Na, Sae Jung |
author_sort | Lee, Yeongjoo |
collection | PubMed |
description | In this presented case, a 77-year-old woman with an implanted prosthesis and ongoing knee pain underwent a bone scan using (99m)Tc-hydroxydiphosphonate (HDP) in suspicion for bone infection. An incidental finding from this scan revealed diffuse cardiac uptake, necessitating further diagnostic procedures to exclude the possibility of cardiac amyloidosis. In the subsequent (99m)Tc-3,3-diphosphono-1,2-propanodicarboxylic acid (DPD) scan and SPECT images, no perceptible cardiac uptake was observed at all. Upon retrospective review of the patient’s medical records, she received 1000 mg of ferric carboxymaltose for iron-deficient anemia the day before the (99m)Tc-HDP bone scan. Therefore, it was assumed that the diffuse and temporary cardiac activity was due to the transient iron overload. We present and share these bone scan images in order to avoid possible future misinterpretation of cardiac amyloidosis. |
format | Online Article Text |
id | pubmed-10647204 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-106472042023-10-30 Diffuse Cardiac Uptake Misdiagnosed as Cardiac Amyloidosis in Bone Scan Lee, Yeongjoo Jang, Jaehyuk Na, Sae Jung Diagnostics (Basel) Interesting Images In this presented case, a 77-year-old woman with an implanted prosthesis and ongoing knee pain underwent a bone scan using (99m)Tc-hydroxydiphosphonate (HDP) in suspicion for bone infection. An incidental finding from this scan revealed diffuse cardiac uptake, necessitating further diagnostic procedures to exclude the possibility of cardiac amyloidosis. In the subsequent (99m)Tc-3,3-diphosphono-1,2-propanodicarboxylic acid (DPD) scan and SPECT images, no perceptible cardiac uptake was observed at all. Upon retrospective review of the patient’s medical records, she received 1000 mg of ferric carboxymaltose for iron-deficient anemia the day before the (99m)Tc-HDP bone scan. Therefore, it was assumed that the diffuse and temporary cardiac activity was due to the transient iron overload. We present and share these bone scan images in order to avoid possible future misinterpretation of cardiac amyloidosis. MDPI 2023-10-30 /pmc/articles/PMC10647204/ /pubmed/37958238 http://dx.doi.org/10.3390/diagnostics13213342 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Interesting Images Lee, Yeongjoo Jang, Jaehyuk Na, Sae Jung Diffuse Cardiac Uptake Misdiagnosed as Cardiac Amyloidosis in Bone Scan |
title | Diffuse Cardiac Uptake Misdiagnosed as Cardiac Amyloidosis in Bone Scan |
title_full | Diffuse Cardiac Uptake Misdiagnosed as Cardiac Amyloidosis in Bone Scan |
title_fullStr | Diffuse Cardiac Uptake Misdiagnosed as Cardiac Amyloidosis in Bone Scan |
title_full_unstemmed | Diffuse Cardiac Uptake Misdiagnosed as Cardiac Amyloidosis in Bone Scan |
title_short | Diffuse Cardiac Uptake Misdiagnosed as Cardiac Amyloidosis in Bone Scan |
title_sort | diffuse cardiac uptake misdiagnosed as cardiac amyloidosis in bone scan |
topic | Interesting Images |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647204/ https://www.ncbi.nlm.nih.gov/pubmed/37958238 http://dx.doi.org/10.3390/diagnostics13213342 |
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