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Diffuse Cardiac Uptake Misdiagnosed as Cardiac Amyloidosis in Bone Scan

In this presented case, a 77-year-old woman with an implanted prosthesis and ongoing knee pain underwent a bone scan using (99m)Tc-hydroxydiphosphonate (HDP) in suspicion for bone infection. An incidental finding from this scan revealed diffuse cardiac uptake, necessitating further diagnostic proced...

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Detalles Bibliográficos
Autores principales: Lee, Yeongjoo, Jang, Jaehyuk, Na, Sae Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647204/
https://www.ncbi.nlm.nih.gov/pubmed/37958238
http://dx.doi.org/10.3390/diagnostics13213342
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author Lee, Yeongjoo
Jang, Jaehyuk
Na, Sae Jung
author_facet Lee, Yeongjoo
Jang, Jaehyuk
Na, Sae Jung
author_sort Lee, Yeongjoo
collection PubMed
description In this presented case, a 77-year-old woman with an implanted prosthesis and ongoing knee pain underwent a bone scan using (99m)Tc-hydroxydiphosphonate (HDP) in suspicion for bone infection. An incidental finding from this scan revealed diffuse cardiac uptake, necessitating further diagnostic procedures to exclude the possibility of cardiac amyloidosis. In the subsequent (99m)Tc-3,3-diphosphono-1,2-propanodicarboxylic acid (DPD) scan and SPECT images, no perceptible cardiac uptake was observed at all. Upon retrospective review of the patient’s medical records, she received 1000 mg of ferric carboxymaltose for iron-deficient anemia the day before the (99m)Tc-HDP bone scan. Therefore, it was assumed that the diffuse and temporary cardiac activity was due to the transient iron overload. We present and share these bone scan images in order to avoid possible future misinterpretation of cardiac amyloidosis.
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spelling pubmed-106472042023-10-30 Diffuse Cardiac Uptake Misdiagnosed as Cardiac Amyloidosis in Bone Scan Lee, Yeongjoo Jang, Jaehyuk Na, Sae Jung Diagnostics (Basel) Interesting Images In this presented case, a 77-year-old woman with an implanted prosthesis and ongoing knee pain underwent a bone scan using (99m)Tc-hydroxydiphosphonate (HDP) in suspicion for bone infection. An incidental finding from this scan revealed diffuse cardiac uptake, necessitating further diagnostic procedures to exclude the possibility of cardiac amyloidosis. In the subsequent (99m)Tc-3,3-diphosphono-1,2-propanodicarboxylic acid (DPD) scan and SPECT images, no perceptible cardiac uptake was observed at all. Upon retrospective review of the patient’s medical records, she received 1000 mg of ferric carboxymaltose for iron-deficient anemia the day before the (99m)Tc-HDP bone scan. Therefore, it was assumed that the diffuse and temporary cardiac activity was due to the transient iron overload. We present and share these bone scan images in order to avoid possible future misinterpretation of cardiac amyloidosis. MDPI 2023-10-30 /pmc/articles/PMC10647204/ /pubmed/37958238 http://dx.doi.org/10.3390/diagnostics13213342 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Interesting Images
Lee, Yeongjoo
Jang, Jaehyuk
Na, Sae Jung
Diffuse Cardiac Uptake Misdiagnosed as Cardiac Amyloidosis in Bone Scan
title Diffuse Cardiac Uptake Misdiagnosed as Cardiac Amyloidosis in Bone Scan
title_full Diffuse Cardiac Uptake Misdiagnosed as Cardiac Amyloidosis in Bone Scan
title_fullStr Diffuse Cardiac Uptake Misdiagnosed as Cardiac Amyloidosis in Bone Scan
title_full_unstemmed Diffuse Cardiac Uptake Misdiagnosed as Cardiac Amyloidosis in Bone Scan
title_short Diffuse Cardiac Uptake Misdiagnosed as Cardiac Amyloidosis in Bone Scan
title_sort diffuse cardiac uptake misdiagnosed as cardiac amyloidosis in bone scan
topic Interesting Images
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647204/
https://www.ncbi.nlm.nih.gov/pubmed/37958238
http://dx.doi.org/10.3390/diagnostics13213342
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