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A Panoramic X-ray as a Supportive Diagnostic Tool for the Screening of Osteoporosis in Patients with Hemophilia A and B
Background: Hemophilia is associated with an increased risk of developing osteoporosis and osteopenia. The aim of the study was to interpret the usefulness of fractal analysis of the trabecular bone of the mandible (FD) and selected radiomorphic indices (the antegonial index (AI) and Klemetti index...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647299/ https://www.ncbi.nlm.nih.gov/pubmed/37959366 http://dx.doi.org/10.3390/jcm12216901 |
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author | Czajkowska, Sylwia Rupa-Matysek, Joanna Nijakowski, Kacper Gil, Lidia Surdacka, Anna Kulczyk, Tomasz |
author_facet | Czajkowska, Sylwia Rupa-Matysek, Joanna Nijakowski, Kacper Gil, Lidia Surdacka, Anna Kulczyk, Tomasz |
author_sort | Czajkowska, Sylwia |
collection | PubMed |
description | Background: Hemophilia is associated with an increased risk of developing osteoporosis and osteopenia. The aim of the study was to interpret the usefulness of fractal analysis of the trabecular bone of the mandible (FD) and selected radiomorphic indices (the antegonial index (AI) and Klemetti index (KI)) to assess the risk of reduced bone mineral density (BMD) in patients with hemophilia A/B. Methods: The study group consisted of 50 patients with type A/B hemophilia. The control group consisted of 25 males without congenital bleeding disorders. The patients had a panoramic radiograph taken with the same X-ray machine (Vistapano S, Durr Dental, Bietigheim-Bissingen, Germany). The AudaXCeph software (Audax d.o.o., Ljubljana, Slovenia) was used to evaluate the AI index, and the ImageJ, software with a specially prepared script, was used to evaluate the FD. The mandibular cortex was assessed distal to the mental foramen using the Klemetti index. Results: There were no statistically significant differences between the AI, KI and FD values between the study group and the control group. Conclusions: This study indicated the lack of usefulness of AI, KI and fractal analysis in identifying patients with hemophilia at risk of reduced bone mass. |
format | Online Article Text |
id | pubmed-10647299 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-106472992023-11-02 A Panoramic X-ray as a Supportive Diagnostic Tool for the Screening of Osteoporosis in Patients with Hemophilia A and B Czajkowska, Sylwia Rupa-Matysek, Joanna Nijakowski, Kacper Gil, Lidia Surdacka, Anna Kulczyk, Tomasz J Clin Med Article Background: Hemophilia is associated with an increased risk of developing osteoporosis and osteopenia. The aim of the study was to interpret the usefulness of fractal analysis of the trabecular bone of the mandible (FD) and selected radiomorphic indices (the antegonial index (AI) and Klemetti index (KI)) to assess the risk of reduced bone mineral density (BMD) in patients with hemophilia A/B. Methods: The study group consisted of 50 patients with type A/B hemophilia. The control group consisted of 25 males without congenital bleeding disorders. The patients had a panoramic radiograph taken with the same X-ray machine (Vistapano S, Durr Dental, Bietigheim-Bissingen, Germany). The AudaXCeph software (Audax d.o.o., Ljubljana, Slovenia) was used to evaluate the AI index, and the ImageJ, software with a specially prepared script, was used to evaluate the FD. The mandibular cortex was assessed distal to the mental foramen using the Klemetti index. Results: There were no statistically significant differences between the AI, KI and FD values between the study group and the control group. Conclusions: This study indicated the lack of usefulness of AI, KI and fractal analysis in identifying patients with hemophilia at risk of reduced bone mass. MDPI 2023-11-02 /pmc/articles/PMC10647299/ /pubmed/37959366 http://dx.doi.org/10.3390/jcm12216901 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Czajkowska, Sylwia Rupa-Matysek, Joanna Nijakowski, Kacper Gil, Lidia Surdacka, Anna Kulczyk, Tomasz A Panoramic X-ray as a Supportive Diagnostic Tool for the Screening of Osteoporosis in Patients with Hemophilia A and B |
title | A Panoramic X-ray as a Supportive Diagnostic Tool for the Screening of Osteoporosis in Patients with Hemophilia A and B |
title_full | A Panoramic X-ray as a Supportive Diagnostic Tool for the Screening of Osteoporosis in Patients with Hemophilia A and B |
title_fullStr | A Panoramic X-ray as a Supportive Diagnostic Tool for the Screening of Osteoporosis in Patients with Hemophilia A and B |
title_full_unstemmed | A Panoramic X-ray as a Supportive Diagnostic Tool for the Screening of Osteoporosis in Patients with Hemophilia A and B |
title_short | A Panoramic X-ray as a Supportive Diagnostic Tool for the Screening of Osteoporosis in Patients with Hemophilia A and B |
title_sort | panoramic x-ray as a supportive diagnostic tool for the screening of osteoporosis in patients with hemophilia a and b |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647299/ https://www.ncbi.nlm.nih.gov/pubmed/37959366 http://dx.doi.org/10.3390/jcm12216901 |
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