Cargando…

Preparation of Azoxystrobin-Zinc Metal–Organic Framework/Biomass Charcoal Composite Materials and Application in the Prevention and Control of Gray Mold in Tomato

In order to reduce the use of fungicide and ensure food safety, it is necessary to develop fungicide with low toxicity and high efficiency to reduce residues. Azoxystrobin (AZOX), which is derived from mushrooms, is an excellent choice. However, conventional AZOX release is difficult to regulate. In...

Descripción completa

Detalles Bibliográficos
Autores principales: Han, Xiao, Qian, Yinjie, Li, Jiapeng, Zhang, Zhongkai, Guo, Jinbo, Zhang, Ning, Liu, Longyu, Cheng, Zhiqiang, Yu, Xiaobin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647336/
https://www.ncbi.nlm.nih.gov/pubmed/37958590
http://dx.doi.org/10.3390/ijms242115609
_version_ 1785135083317886976
author Han, Xiao
Qian, Yinjie
Li, Jiapeng
Zhang, Zhongkai
Guo, Jinbo
Zhang, Ning
Liu, Longyu
Cheng, Zhiqiang
Yu, Xiaobin
author_facet Han, Xiao
Qian, Yinjie
Li, Jiapeng
Zhang, Zhongkai
Guo, Jinbo
Zhang, Ning
Liu, Longyu
Cheng, Zhiqiang
Yu, Xiaobin
author_sort Han, Xiao
collection PubMed
description In order to reduce the use of fungicide and ensure food safety, it is necessary to develop fungicide with low toxicity and high efficiency to reduce residues. Azoxystrobin (AZOX), which is derived from mushrooms, is an excellent choice. However, conventional AZOX release is difficult to regulate. In this paper, a pH-responsive fungicide delivery system for the preparation of AZOX by impregnation method was reported. The Zinc metal–organic framework/Biomass charcoal (ZIF-8/BC) support was first prepared, and subsequently, the AZOX-ZIF-8/BC nano fungicide was prepared by adsorption of AZOX onto ZIF-8/BC by dipping. Gray mold, caused by Botrytis cinerea, is one of the most important crop diseases worldwide. AZOX-ZIF-8/BC could respond to oxalic acid produced by Botrytis cinerea to release loaded AZOX. When pH = 4.8, it was 48.42% faster than when pH = 8.2. The loading of AZOX on ZIF-8/BC was 19.83%. In vitro and pot experiments showed that AZOX-ZIF-8/BC had significant fungicidal activity, and 300 mg/L concentration of AZOX-ZIF-8-BC could be considered as a safe and effective control of Botrytis cinerea. The above results indicated that the prepared AZOX-ZIF-8/BC not only exhibited good drug efficacy but also demonstrated pH-responsive fungicide release.
format Online
Article
Text
id pubmed-10647336
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-106473362023-10-26 Preparation of Azoxystrobin-Zinc Metal–Organic Framework/Biomass Charcoal Composite Materials and Application in the Prevention and Control of Gray Mold in Tomato Han, Xiao Qian, Yinjie Li, Jiapeng Zhang, Zhongkai Guo, Jinbo Zhang, Ning Liu, Longyu Cheng, Zhiqiang Yu, Xiaobin Int J Mol Sci Article In order to reduce the use of fungicide and ensure food safety, it is necessary to develop fungicide with low toxicity and high efficiency to reduce residues. Azoxystrobin (AZOX), which is derived from mushrooms, is an excellent choice. However, conventional AZOX release is difficult to regulate. In this paper, a pH-responsive fungicide delivery system for the preparation of AZOX by impregnation method was reported. The Zinc metal–organic framework/Biomass charcoal (ZIF-8/BC) support was first prepared, and subsequently, the AZOX-ZIF-8/BC nano fungicide was prepared by adsorption of AZOX onto ZIF-8/BC by dipping. Gray mold, caused by Botrytis cinerea, is one of the most important crop diseases worldwide. AZOX-ZIF-8/BC could respond to oxalic acid produced by Botrytis cinerea to release loaded AZOX. When pH = 4.8, it was 48.42% faster than when pH = 8.2. The loading of AZOX on ZIF-8/BC was 19.83%. In vitro and pot experiments showed that AZOX-ZIF-8/BC had significant fungicidal activity, and 300 mg/L concentration of AZOX-ZIF-8-BC could be considered as a safe and effective control of Botrytis cinerea. The above results indicated that the prepared AZOX-ZIF-8/BC not only exhibited good drug efficacy but also demonstrated pH-responsive fungicide release. MDPI 2023-10-26 /pmc/articles/PMC10647336/ /pubmed/37958590 http://dx.doi.org/10.3390/ijms242115609 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Han, Xiao
Qian, Yinjie
Li, Jiapeng
Zhang, Zhongkai
Guo, Jinbo
Zhang, Ning
Liu, Longyu
Cheng, Zhiqiang
Yu, Xiaobin
Preparation of Azoxystrobin-Zinc Metal–Organic Framework/Biomass Charcoal Composite Materials and Application in the Prevention and Control of Gray Mold in Tomato
title Preparation of Azoxystrobin-Zinc Metal–Organic Framework/Biomass Charcoal Composite Materials and Application in the Prevention and Control of Gray Mold in Tomato
title_full Preparation of Azoxystrobin-Zinc Metal–Organic Framework/Biomass Charcoal Composite Materials and Application in the Prevention and Control of Gray Mold in Tomato
title_fullStr Preparation of Azoxystrobin-Zinc Metal–Organic Framework/Biomass Charcoal Composite Materials and Application in the Prevention and Control of Gray Mold in Tomato
title_full_unstemmed Preparation of Azoxystrobin-Zinc Metal–Organic Framework/Biomass Charcoal Composite Materials and Application in the Prevention and Control of Gray Mold in Tomato
title_short Preparation of Azoxystrobin-Zinc Metal–Organic Framework/Biomass Charcoal Composite Materials and Application in the Prevention and Control of Gray Mold in Tomato
title_sort preparation of azoxystrobin-zinc metal–organic framework/biomass charcoal composite materials and application in the prevention and control of gray mold in tomato
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647336/
https://www.ncbi.nlm.nih.gov/pubmed/37958590
http://dx.doi.org/10.3390/ijms242115609
work_keys_str_mv AT hanxiao preparationofazoxystrobinzincmetalorganicframeworkbiomasscharcoalcompositematerialsandapplicationinthepreventionandcontrolofgraymoldintomato
AT qianyinjie preparationofazoxystrobinzincmetalorganicframeworkbiomasscharcoalcompositematerialsandapplicationinthepreventionandcontrolofgraymoldintomato
AT lijiapeng preparationofazoxystrobinzincmetalorganicframeworkbiomasscharcoalcompositematerialsandapplicationinthepreventionandcontrolofgraymoldintomato
AT zhangzhongkai preparationofazoxystrobinzincmetalorganicframeworkbiomasscharcoalcompositematerialsandapplicationinthepreventionandcontrolofgraymoldintomato
AT guojinbo preparationofazoxystrobinzincmetalorganicframeworkbiomasscharcoalcompositematerialsandapplicationinthepreventionandcontrolofgraymoldintomato
AT zhangning preparationofazoxystrobinzincmetalorganicframeworkbiomasscharcoalcompositematerialsandapplicationinthepreventionandcontrolofgraymoldintomato
AT liulongyu preparationofazoxystrobinzincmetalorganicframeworkbiomasscharcoalcompositematerialsandapplicationinthepreventionandcontrolofgraymoldintomato
AT chengzhiqiang preparationofazoxystrobinzincmetalorganicframeworkbiomasscharcoalcompositematerialsandapplicationinthepreventionandcontrolofgraymoldintomato
AT yuxiaobin preparationofazoxystrobinzincmetalorganicframeworkbiomasscharcoalcompositematerialsandapplicationinthepreventionandcontrolofgraymoldintomato