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Genetic Predisposition to Elevated Levels of Circulating ADAM17 Is Associated with the Risk of Severe COVID-19

High levels of ADAM17 activity have emerged as an important mediator in severe COVID-19. This study aims to characterize eventual causal relationships between ADAM17 and COVID-19. Using Mendelian randomization analyses, we examined the causal effects of circulating ADAM17 on COVID-19 outcomes using...

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Detalles Bibliográficos
Autores principales: Pan, Mengyu, Goncalves, Isabel, Edsfeldt, Andreas, Sun, Jiangming, Swärd, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647461/
https://www.ncbi.nlm.nih.gov/pubmed/37958866
http://dx.doi.org/10.3390/ijms242115879

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