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Recent Advances in SARS-CoV-2 Main Protease Inhibitors: From Nirmatrelvir to Future Perspectives
The main protease (M(pro)) plays a pivotal role in the replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and is considered a highly conserved viral target. Disruption of the catalytic activity of M(pro) produces a detrimental effect on the course of the infection, making th...
Autores principales: | Citarella, Andrea, Dimasi, Alessandro, Moi, Davide, Passarella, Daniele, Scala, Angela, Piperno, Anna, Micale, Nicola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647625/ https://www.ncbi.nlm.nih.gov/pubmed/37759739 http://dx.doi.org/10.3390/biom13091339 |
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