Cargando…

Melatonin Exerts Prominent, Differential Epidermal and Dermal Anti-Aging Properties in Aged Human Eyelid Skin Ex Vivo

Human skin aging is associated with functional deterioration on multiple levels of physiology, necessitating the development of effective skin senotherapeutics. The well-tolerated neurohormone melatonin unfolds anti-aging properties in vitro and in vivo, but it remains unclear whether these effects...

Descripción completa

Detalles Bibliográficos
Autores principales:	Samra, Tara, Gomez-Gomez, Tatiana, Linowiecka, Kinga, Akhundlu, Aysun, Lopez de Mendoza, Gabriella, Gompels, Matthew, Lee, Wendy W., Gherardini, Jennifer, Chéret, Jérémy, Paus, Ralf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647640/ https://www.ncbi.nlm.nih.gov/pubmed/37958946 http://dx.doi.org/10.3390/ijms242115963

Ejemplares similares

Melatonin: A Potential Regulator of DNA Methylation
por: Linowiecka, Kinga, et al.
Publicado: (2023)

mTORC1 activity negatively regulates human hair follicle growth and pigmentation
por: Suzuki, Takahiro, et al.
Publicado: (2023)

Ultraviolet Radiation-Induced Mitochondrial Disturbances Are Attenuated by Metabolites of Melatonin in Human Epidermal Keratinocytes
por: Holtkamp, Chantal E., et al.
Publicado: (2023)

Towards developing an organotypic model for the preclinical study and manipulation of human hair matrix-dermal papilla interactions
por: Platt, Christopher I., et al.
Publicado: (2021)

Age, Diet and Epidermal Signaling Modulate Dermal Fibroblasts’ Adipogenic Potential
por: Walendzik, Katarzyna, et al.
Publicado: (2020)

Tissue-resident macrophages can be generated de novo in adult human skin from resident progenitor cells during substance P-mediated neurogenic inflammation ex vivo
por: Gherardini, Jennifer, et al.
Publicado: (2020)

Age-Related Changes in the Regenerative Potential of Adipose-Derived Stem Cells Isolated from the Prominent Fat Pads in Human Lower Eyelids
por: Ye, Xinhai, et al.
Publicado: (2016)

Epidermal and Dermal Hallmarks of Photoaging are Prevented by Treatment with Night Serum Containing Melatonin, Bakuchiol, and Ascorbyl Tetraisopalmitate: In Vitro and Ex Vivo Studies
por: Narda, Mridvika, et al.
Publicado: (2020)

Eyelid Crease Height Affects the Evaluation of Age-related Changes in the Eyelids
por: Akita, Shinsuke, et al.
Publicado: (2021)

A Cell Membrane-Level Approach to Cicatricial Alopecia Management: Is Caveolin-1 a Viable Therapeutic Target in Frontal Fibrosing Alopecia?
por: Jozic, Ivan, et al.
Publicado: (2021)

Prominent Hyperproinsulinemia in a Middle Age Patient
por: Yoshino, Hiroshi, et al.
Publicado: (2021)

Quantitative 3-dimensional Geometry of the Aging Eyelids
por: Flores, Cristina A., et al.
Publicado: (2019)

Prominent dermal accumulation of Russell bodies underlying pseudocarcinomatous hyperplasia with fungal infection
por: Noda, Tatsuhiro, et al.
Publicado: (2023)

Eyelid and Vaginal Adhesions as Severe Sequelae of Toxic Epidermal Necrolysis
por: Suzuki, Kaori, et al.
Publicado: (2023)

Differential gene screening and bioinformatics analysis of epidermal stem cells and dermal fibroblasts during skin aging
por: Hu, Weisheng, et al.
Publicado: (2022)

Melanogenesis Is Directly Affected by Metabolites of Melatonin in Human Melanoma Cells
por: Möller, Jack K. S., et al.
Publicado: (2023)

Preliminary evidence that light through the eyelids can suppress melatonin and phase shift dim light melatonin onset
por: Figueiro, Mariana G, et al.
Publicado: (2012)

A Case of Inflammatory Linear Verrucous Epidermal Nevus on the Upper Eyelid
por: Nakai, Noriaki, et al.
Publicado: (2015)

Systematized Epidermal Nevus Syndrome Involving the Upper and Lower Eyelids Bilaterally
por: Biçer, Özlem, et al.
Publicado: (2021)

Paradoxical aging in HIV: immune senescence of B Cells is most prominent in young age
por: Rinaldi, Stefano, et al.
Publicado: (2017)

Prevention and Treatment of Chemotherapy-Induced Alopecia: What Is Available and What Is Coming?
por: Wikramanayake, Tongyu C., et al.
Publicado: (2023)

Case of Pleomorphic Dermal Sarcoma of the Eyelid Treated with Micrographic Surgery and Secondary Intention Healing
por: Kim, Jung-In, et al.
Publicado: (2016)

Bovine Acellular Dermal Matrix for Levator Lengthening in Thyroid-Related Upper-Eyelid Retraction
por: Sun, Jing, et al.
Publicado: (2018)

Transepidermal UV radiation of scalp skin ex vivo induces hair follicle damage that is alleviated by the topical treatment with caffeine
por: Gherardini, Jennifer, et al.
Publicado: (2019)

Pulsing blue light through closed eyelids: effects on acute melatonin suppression and phase shifting of dim light melatonin onset
por: Figueiro, Mariana G, et al.
Publicado: (2014)

Melatonin, immune function and aging
por: Srinivasan, V, et al.
Publicado: (2005)

Melatonin and human skin aging
por: Kleszczynski, Konrad, et al.
Publicado: (2012)

Role of Melatonin in Angiotensin and Aging
por: Sehirli, Ahmet Ozer, et al.
Publicado: (2021)

Impaired burrowing is the most prominent behavioral deficit of aging htau mice
por: Geiszler, Philippine Camilla, et al.
Publicado: (2016)

Vitamin C Transporters and Their Implications in Carcinogenesis
por: Linowiecka, Kinga, et al.
Publicado: (2020)

Treatment of the Ageing Hand with Dermal Fillers
por: Kühne, Ulrich, et al.
Publicado: (2012)

Quantitative nanohistology of aging dermal collagen
por: Huang, Sophia, et al.
Publicado: (2023)

Skin aging from mechanisms to interventions: focusing on dermal aging
por: Shin, Sun Hye, et al.
Publicado: (2023)

Melatonin and age‐related cardiovascular diseases
por: Zhong, Jiayu, et al.
Publicado: (2018)

Age Associated Decrease of MT-1 Melatonin Receptor in Human Dermal Skin Fibroblasts Impairs Protection Against UV-Induced DNA Damage
por: Dong, Kelly, et al.
Publicado: (2020)

Dissociated human dermal papilla cells induce hair follicle neogenesis in grafted dermal-epidermal composites
por: Thangapazham, Rajesh L., et al.
Publicado: (2013)

The effect of aging in primary human dermal fibroblasts
por: Lago, Juliana Carvalhães, et al.
Publicado: (2019)

Molecular Mechanisms of Dermal Aging and Antiaging Approaches
por: Shin, Jung-Won, et al.
Publicado: (2019)

IgG4 autoantibodies induce dermal–epidermal separation
por: Mihai, Sidonia, et al.
Publicado: (2007)

Dermal Contributions to Human Interfollicular Epidermal Architecture and Self-Renewal
por: Lawlor, Kynan T., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_mv6i9lssj48h55g7pe0i384pkl