Total Synthesis of Nicrophorusamide A and Structural Disproof of the Proposed Noursamycin A

Total synthesis of the proposed noursamycin A has been accomplished, which disproves the original structural assignments. The synthetic strategy described herein has also been employed in the first total synthesis of nicrophorusamide A, a cyclopeptide that is structurally related to noursamycin A.

Detalles Bibliográficos
Autores principales: Liao, Xiaoyun, Li, Shupeng, Guo, Yian, Ye, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647733/
https://www.ncbi.nlm.nih.gov/pubmed/37959861
http://dx.doi.org/10.3390/molecules28217442
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author Liao, Xiaoyun
Li, Shupeng
Guo, Yian
Ye, Tao
author_facet Liao, Xiaoyun
Li, Shupeng
Guo, Yian
Ye, Tao
author_sort Liao, Xiaoyun
collection PubMed
description Total synthesis of the proposed noursamycin A has been accomplished, which disproves the original structural assignments. The synthetic strategy described herein has also been employed in the first total synthesis of nicrophorusamide A, a cyclopeptide that is structurally related to noursamycin A.
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spelling pubmed-106477332023-11-06 Total Synthesis of Nicrophorusamide A and Structural Disproof of the Proposed Noursamycin A Liao, Xiaoyun Li, Shupeng Guo, Yian Ye, Tao Molecules Article Total synthesis of the proposed noursamycin A has been accomplished, which disproves the original structural assignments. The synthetic strategy described herein has also been employed in the first total synthesis of nicrophorusamide A, a cyclopeptide that is structurally related to noursamycin A. MDPI 2023-11-06 /pmc/articles/PMC10647733/ /pubmed/37959861 http://dx.doi.org/10.3390/molecules28217442 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Liao, Xiaoyun
Li, Shupeng
Guo, Yian
Ye, Tao
Total Synthesis of Nicrophorusamide A and Structural Disproof of the Proposed Noursamycin A
title Total Synthesis of Nicrophorusamide A and Structural Disproof of the Proposed Noursamycin A
title_full Total Synthesis of Nicrophorusamide A and Structural Disproof of the Proposed Noursamycin A
title_fullStr Total Synthesis of Nicrophorusamide A and Structural Disproof of the Proposed Noursamycin A
title_full_unstemmed Total Synthesis of Nicrophorusamide A and Structural Disproof of the Proposed Noursamycin A
title_short Total Synthesis of Nicrophorusamide A and Structural Disproof of the Proposed Noursamycin A
title_sort total synthesis of nicrophorusamide a and structural disproof of the proposed noursamycin a
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647733/
https://www.ncbi.nlm.nih.gov/pubmed/37959861
http://dx.doi.org/10.3390/molecules28217442
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AT guoyian totalsynthesisofnicrophorusamideaandstructuraldisproofoftheproposednoursamycina
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