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PHB2 Alleviates Neurotoxicity of Prion Peptide PrP(106–126) via PINK1/Parkin-Dependent Mitophagy

Prion diseases are a group of neurodegenerative diseases characterized by mitochondrial dysfunction and neuronal death. Mitophagy is a selective form of macroautophagy that clears injured mitochondria. Prohibitin 2 (PHB2) has been identified as a novel inner membrane mitophagy receptor that mediates...

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Detalles Bibliográficos
Autores principales: Zheng, Xiaohui, Liu, Kun, Xie, Qingqing, Xin, Hangkuo, Chen, Wei, Lin, Shengyu, Feng, Danqi, Zhu, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647768/
https://www.ncbi.nlm.nih.gov/pubmed/37958902
http://dx.doi.org/10.3390/ijms242115919