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Association between Dietary Acid Load and Hypertension in Chinese Adults: Analysis of the China Health and Nutrition Survey (2009)

(1) Background: Current studies show conflicting results regarding the relationship between dietary acid load (DAL) and blood pressure. (2) Methods: The study used data from the Chinese Health and Nutrition Survey (CHNS) 2009. DAL was assessed on the basis of potential renal acid load (PRAL) and net...

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Autores principales: Lin, Feng, Zhang, Min, Wang, Ruoyu, Sun, Meng, Zhang, Zongfeng, Qiao, Yanjiang, Zhang, Zhaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647800/
https://www.ncbi.nlm.nih.gov/pubmed/37960317
http://dx.doi.org/10.3390/nu15214664
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author Lin, Feng
Zhang, Min
Wang, Ruoyu
Sun, Meng
Zhang, Zongfeng
Qiao, Yanjiang
Zhang, Zhaofeng
author_facet Lin, Feng
Zhang, Min
Wang, Ruoyu
Sun, Meng
Zhang, Zongfeng
Qiao, Yanjiang
Zhang, Zhaofeng
author_sort Lin, Feng
collection PubMed
description (1) Background: Current studies show conflicting results regarding the relationship between dietary acid load (DAL) and blood pressure. (2) Methods: The study used data from the Chinese Health and Nutrition Survey (CHNS) 2009. DAL was assessed on the basis of potential renal acid load (PRAL) and net endogenous acid production (NEAP). To examine the link between DAL and the risk of hypertension, a multivariate logistic regression model was utilized. (3) Results: A total of 7912 subjects were enrolled in the study, of whom 2133 participants had hypertension, a prevalence of 27.0%. After accounting for potential covariates, higher PRAL and NEAP scores were associated with a greater likelihood of developing hypertension, with ORs of 1.34 (95% CI, 1.10–1.62) and 1.29 (95% CI, 1.09–1.53) for PRAL and NEAP scores in Q4, respectively, compared with Q1. In the male group, PRAL and NEAP scores were positively linked to hypertension risk, with ORs of 1.33 (95% CI, 1.06–1.67) and 1.46 (95% CI, 1.14–1.85) for PRAL and NEAP scores in Q4, respectively, compared with Q1, while no significant associations were observed in the female group. Correlations between PRAL scores and hypertension risk lacked significance in the subgroup analyses for participants aged <60 years. There was a significant nonlinear connection observed in the dose–response relationship between DAL (based on PRAL) and hypertension; (4) Conclusions: In Chinese adults, higher PRAL and NEAP scores were positively linked to hypertension risk. This implies that a diet with a low DAL may be a favorable dietary pattern for lowering blood pressure.
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spelling pubmed-106478002023-11-03 Association between Dietary Acid Load and Hypertension in Chinese Adults: Analysis of the China Health and Nutrition Survey (2009) Lin, Feng Zhang, Min Wang, Ruoyu Sun, Meng Zhang, Zongfeng Qiao, Yanjiang Zhang, Zhaofeng Nutrients Article (1) Background: Current studies show conflicting results regarding the relationship between dietary acid load (DAL) and blood pressure. (2) Methods: The study used data from the Chinese Health and Nutrition Survey (CHNS) 2009. DAL was assessed on the basis of potential renal acid load (PRAL) and net endogenous acid production (NEAP). To examine the link between DAL and the risk of hypertension, a multivariate logistic regression model was utilized. (3) Results: A total of 7912 subjects were enrolled in the study, of whom 2133 participants had hypertension, a prevalence of 27.0%. After accounting for potential covariates, higher PRAL and NEAP scores were associated with a greater likelihood of developing hypertension, with ORs of 1.34 (95% CI, 1.10–1.62) and 1.29 (95% CI, 1.09–1.53) for PRAL and NEAP scores in Q4, respectively, compared with Q1. In the male group, PRAL and NEAP scores were positively linked to hypertension risk, with ORs of 1.33 (95% CI, 1.06–1.67) and 1.46 (95% CI, 1.14–1.85) for PRAL and NEAP scores in Q4, respectively, compared with Q1, while no significant associations were observed in the female group. Correlations between PRAL scores and hypertension risk lacked significance in the subgroup analyses for participants aged <60 years. There was a significant nonlinear connection observed in the dose–response relationship between DAL (based on PRAL) and hypertension; (4) Conclusions: In Chinese adults, higher PRAL and NEAP scores were positively linked to hypertension risk. This implies that a diet with a low DAL may be a favorable dietary pattern for lowering blood pressure. MDPI 2023-11-03 /pmc/articles/PMC10647800/ /pubmed/37960317 http://dx.doi.org/10.3390/nu15214664 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lin, Feng
Zhang, Min
Wang, Ruoyu
Sun, Meng
Zhang, Zongfeng
Qiao, Yanjiang
Zhang, Zhaofeng
Association between Dietary Acid Load and Hypertension in Chinese Adults: Analysis of the China Health and Nutrition Survey (2009)
title Association between Dietary Acid Load and Hypertension in Chinese Adults: Analysis of the China Health and Nutrition Survey (2009)
title_full Association between Dietary Acid Load and Hypertension in Chinese Adults: Analysis of the China Health and Nutrition Survey (2009)
title_fullStr Association between Dietary Acid Load and Hypertension in Chinese Adults: Analysis of the China Health and Nutrition Survey (2009)
title_full_unstemmed Association between Dietary Acid Load and Hypertension in Chinese Adults: Analysis of the China Health and Nutrition Survey (2009)
title_short Association between Dietary Acid Load and Hypertension in Chinese Adults: Analysis of the China Health and Nutrition Survey (2009)
title_sort association between dietary acid load and hypertension in chinese adults: analysis of the china health and nutrition survey (2009)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647800/
https://www.ncbi.nlm.nih.gov/pubmed/37960317
http://dx.doi.org/10.3390/nu15214664
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