Cargando…

The Influence of Chirality on the β-Amino-Acid Naphthalenediimides/G-Quadruplex DNA Interaction

G-quadruplexes (G4s) have been identified as a potential alternative chemotherapy target. A series of eight β-amino acid derived naphthalenediimides (NDI) were screened against a series of oncogenic G4 sequences: c-KIT1, h-TELO, and TBA. Three sets of enantiomers were investigated to further our und...

Descripción completa

Detalles Bibliográficos
Autores principales:	Clowes, Samuel R., Ali, Yusuf, Astley, Olivia R., Răsădean, Dora M., Pantoş, G. Dan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647805/ https://www.ncbi.nlm.nih.gov/pubmed/37959711 http://dx.doi.org/10.3390/molecules28217291

Ejemplares similares

Importance of Chiral Recognition in Designing Metal-Free Ligands for G-Quadruplex DNA
por: Răsădean, Dora M., et al.
Publicado: (2019)

Naphthalenediimide-Linked Bisbenzimidazole Derivatives as Telomeric G-Quadruplex-Stabilizing Ligands with Improved Anticancer Activity
por: Sur, Souvik, et al.
Publicado: (2017)

Mapping the Chiroptical Properties of Local Domains in Thin Films of Chiral Silicon Phthalocyanines by CD Imaging
por: Răsădean, Dora-M., et al.
Publicado: (2020)

Mueller Matrix Polarimetry on Cyanine Dye J-Aggregates
por: Clowes, Samuel R., et al.
Publicado: (2023)

The role of amino acids on supramolecular co-assembly of naphthalenediimide–pyrene based hydrogelators
por: Nelli, Srinivasa Rao, et al.
Publicado: (2018)

Chiral metallohelices enantioselectively target hybrid human telomeric G-quadruplex DNA
por: Zhao, Andong, et al.
Publicado: (2017)

Synthesis and Characterization of Naphthalenediimide-Functionalized Flavin Derivatives
por: Zainalabdeen, Nada, et al.
Publicado: (2013)

Chiral metallo-supramolecular complexes selectively recognize human telomeric G-quadruplex DNA
por: Yu, Haijia, et al.
Publicado: (2008)

Classification of G-Quadruplex DNA on the Basis of the Quadruplex Twist Angle and Planarity of G-Quartets
por: Reshetnikov, R.V., et al.
Publicado: (2010)

Light-Induced Modulation of Chiral Functions in G-Quadruplex–Photochrome Systems
por: Dudek, Marta, et al.
Publicado: (2021)

Persistent radical anion polymers based on naphthalenediimide and a vinylene spacer
por: Debnath, Sashi, et al.
Publicado: (2018)

The influencing factors and functions of DNA G‐quadruplexes
por: Yuan, Wen‐Fang, et al.
Publicado: (2020)

Replication of G Quadruplex DNA
por: Lerner, Leticia Koch, et al.
Publicado: (2019)

G-Quadruplex DNA and RNA
por: Yang, Danzhou
Publicado: (2019)

Chiral Ruthenium(II) Polypyridyl Complexes: Stabilization of G-Quadruplex DNA, Inhibition of Telomerase Activity and Cellular Uptake
por: Yu, Qianqian, et al.
Publicado: (2012)

G-Quadruplex binding enantiomers show chiral selective interactions with human telomere
por: Wang, Jiasi, et al.
Publicado: (2014)

Unraveling the Driving Forces in the Self-Assembly of Monodisperse Naphthalenediimide-Oligodimethylsiloxane Block Molecules
por: Berrocal, José Augusto, et al.
Publicado: (2017)

The effects of DNA supercoiling on G-quadruplex formation
por: Sekibo, Doreen A.T., et al.
Publicado: (2017)

π-Stacks of radical-anionic naphthalenediimides in a metal-organic framework
por: Kim, Bongkyeom, et al.
Publicado: (2022)

Mesoscopic model for DNA G-quadruplex unfolding
por: Bergues-Pupo, A. E., et al.
Publicado: (2017)

The Structure and Function of DNA G-Quadruplexes
por: Spiegel, Jochen, et al.
Publicado: (2020)

The Relevance of G-Quadruplexes for DNA Repair
por: Linke, Rebecca, et al.
Publicado: (2021)

How to split a G-quadruplex for DNA detection: new insight into the formation of DNA split G-quadruplex
por: Zhu, Jinbo, et al.
Publicado: (2015)

Design, Synthesis and Evaluation of Bifunctional Acridinine−Naphthalenediimide Redox-Active Conjugates as Antimalarials
por: Dana, Srikanta, et al.
Publicado: (2016)

DNA G-quadruplex structures mould the DNA methylome
por: Mao, Shi-Qing, et al.
Publicado: (2018)

G-quadruplex targeting chemical nucleases as a nonperturbative tool for analysis of cellular G-quadruplex DNA
por: Yu, Zhen, et al.
Publicado: (2021)

Replication Control of Human Telomere G-Quadruplex DNA by G-Quadruplex Ligands Dependent on Solution Environment
por: Takahashi, Shuntaro, et al.
Publicado: (2022)

Using Macrocyclic G‐Quadruplex Ligands to Decipher the Interactions Between Small Molecules and G‐Quadruplex DNA
por: Andréasson, Måns, et al.
Publicado: (2022)

Molecular models for intrastrand DNA G-quadruplexes
por: Fogolari, Federico, et al.
Publicado: (2009)

Detection of G-quadruplex DNA in mammalian cells
por: Henderson, Alexander, et al.
Publicado: (2014)

Folding and misfolding pathways of G-quadruplex DNA
por: Marchand, Adrien, et al.
Publicado: (2016)

Detection of G-quadruplex DNA in mammalian cells
por: Henderson, Alexander, et al.
Publicado: (2017)

Photoresponsive Control of G-Quadruplex DNA Systems
por: Ramos-Soriano, Javier, et al.
Publicado: (2021)

DNA G-Quadruplexes Contribute to CTCF Recruitment
por: Tikhonova, Polina, et al.
Publicado: (2021)

Phase Diagrams of n-Type Low Bandgap Naphthalenediimide-Bithiophene Copolymer Solutions and Blends
por: Fanta, Gada Muleta, et al.
Publicado: (2019)

Long-lived triplet charge-separated state in naphthalenediimide based donor–acceptor systems
por: Aster, Alexander, et al.
Publicado: (2021)

Existence of G-quadruplex structures in promoter region of oncogenes confirmed by G-quadruplex DNA cross-linking strategy
por: Yuan, Libo, et al.
Publicado: (2013)

Spectroscopic data for the G-quadruplex DNA to duplex DNA reaction
por: Mendoza, Oscar, et al.
Publicado: (2015)

Structure and Stability of Human Telomeric G-Quadruplex with Preclinical 9-Amino Acridines
por: Ferreira, Ruben, et al.
Publicado: (2013)

Corrigendum: Existence of G-quadruplex structures in promoter region of oncogenes confirmed by G-quadruplex DNA cross-linking strategy
por: Yuan, Libo, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_s33rap10it0ste7th4vaidil34