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G-Protein-Coupled Receptor 91-Dependent Signalling Does Not Influence Vascular Inflammation and Atherosclerosis in Hyperlipidaemic Mice

The TCA cycle intermediate metabolite ‘succinate’ has been proposed as an inflammatory mediator, influencing autoimmunity and allergic reactions, through ligation to its sensing receptor SUCNR1/GPR91. Whether GPR91-mediated signalling influences the chronic inflammatory process of atherosclerosis ha...

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Detalles Bibliográficos
Autores principales: Griepke, Silke, Trauelsen, Mette, Nilsson, Michelle D., Hansen, Jakob, Steffensen, Lasse B., Schwartz, Thue W., Ketelhuth, Daniel F. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647868/
https://www.ncbi.nlm.nih.gov/pubmed/37947659
http://dx.doi.org/10.3390/cells12212580