Validation of a Molecular Diagnostic Test for Circulating Tumor DNA by Next-Gen Sequencing

A modified version of the PGDx elio(TM) Plasma Resolve assay was validated as a laboratory-developed test (LDT) for clinical use in the Molecular Diagnostics Laboratory at Fox Chase Cancer Center. The test detects single nucleotide variants (SNVs) and small insertions and deletions (indels) in 33 ta...

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Detalles Bibliográficos
Autores principales: Fernandez, Sandra V., Tan, Yin Fei, Rao, Shilpa, Fittipaldi, Patricia, Sheriff, Fathima, Borghaei, Hossein, Dotan, Efrat, Winn, Jennifer S., Edelman, Martin J., Treat, Joseph, Judd, Julia, Alpaugh, R. Katherine, Wang, Y. Lynn, Yu, Jian Q., Wasik, Mariusz, Baldwin, Don A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10648112/
https://www.ncbi.nlm.nih.gov/pubmed/37958763
http://dx.doi.org/10.3390/ijms242115779

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