Novel MAGL Inhibitors Alleviate LPS-Induced Acute Kidney Injury by Inhibiting NLRP3 Inflammatory Vesicles, Modulating Intestinal Flora, Repairing the Intestinal Barrier, and Interfering with Serum Metabolism

Acute kidney injury (AKI) is a complication of a wide range of serious illnesses for which there is still no better therapeutic agent. We demonstrated that M-18C has a favorable inhibitory effect on monoacylglycerol lipase (MAGL), and several studies have demonstrated that nerve inflammation could b...

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Detalles Bibliográficos
Autores principales: Xiang, Haixin, Wang, Yangui, Yang, Lan, Liu, Mingfei, Sun, Chenghong, Gu, Yuchao, Yao, Jingchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10648159/
https://www.ncbi.nlm.nih.gov/pubmed/37959665
http://dx.doi.org/10.3390/molecules28217245

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