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The key cellular senescence related molecule RRM2 regulates prostate cancer progression and resistance to docetaxel treatment

BACKGROUND: Prostate cancer is a leading cause of cancer-related deaths among men worldwide. Docetaxel chemotherapy has proven effective in improving overall survival in patients with castration-resistant prostate cancer (CRPC), but drug resistance remains a considerable clinical challenge. METHODS:...

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Detalles Bibliográficos
Autores principales: Cheng, Bisheng, Li, Lingfeng, Wu, Yongxin, Luo, Tianlong, Tang, Chen, Wang, Qiong, Zhou, Qianghua, Wu, Jilin, Lai, Yiming, Zhu, Dingjun, Du, Tao, Huang, Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10648385/
https://www.ncbi.nlm.nih.gov/pubmed/37968699
http://dx.doi.org/10.1186/s13578-023-01157-6

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