Genomic and Reverse Translational Analysis Discloses a Role for Small GTPase RhoA Signaling in the Pathogenesis of Schizophrenia: Rho-Kinase as a Novel Drug Target

Schizophrenia is one of the most serious psychiatric disorders and is characterized by reductions in both brain volume and spine density in the frontal cortex. RhoA belongs to the RAS homolog (Rho) family and plays critical roles in neuronal development and structural plasticity via Rho-kinase. RhoA...

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Detalles Bibliográficos
Autores principales: Tanaka, Rinako, Yamada, Kiyofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10648424/
https://www.ncbi.nlm.nih.gov/pubmed/37958606
http://dx.doi.org/10.3390/ijms242115623

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10648424/
https://www.ncbi.nlm.nih.gov/pubmed/37958606
http://dx.doi.org/10.3390/ijms242115623

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