Cargando…

A Direct Method for Synthesis of Quinoxalines and Quinazolinones Using Epoxides as Alkyl Precursor

An iodine-mediated one-pot synthesis of pyrrolo/indolo [1,2-a]quinoxalines and quinazolin-4-one via utilizing epoxides as alkyl precursors under metal-free conditions has been described. Both 1-(2-aminophenyl)-pyrrole and 2-aminobenzamide could be applied to this protocol. A total of 33 desired prod...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lv, Xueyan, Lv, Lili, Li, Shichen, Ding, Chengcheng, Yang, Bingchuan, Ma, Chen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10648482/ https://www.ncbi.nlm.nih.gov/pubmed/37959810 http://dx.doi.org/10.3390/molecules28217391

Ejemplares similares

Photoinduced Enhanced Decomposition of TBHP: A Convenient and Greener Pathway for Aqueous Domino Synthesis of Quinazolinones and Quinoxalines
por: Sarma, Daisy, et al.
Publicado: (2021)

N-Alkylation and Aminohydroxylation of 2-Azidobenzenesulfonamide Gives a Pyrrolobenzothiadiazepine Precursor Whereas Attempted N-Alkylation of 2-Azidobenzamide Gives Benzotriazinones and Quinazolinones
por: Hamasharif, Muslih S., et al.
Publicado: (2017)

Iridium-catalysed direct sulfamidation of quinazolinones
por: Feng, Yadong, et al.
Publicado: (2018)

Convergent micro-wave assisted synthesis of quinazolinone and its precursor using the bio-sourced solvent pinane
por: Richieu, Antoine, et al.
Publicado: (2023)

Convenient Synthesis of N-Alkyl-2-(3-phenyl-quinoxalin-2-ylsulfanyl)acetamides and Methyl-2-[2-(3-phenyl-quinoxalin-2-ylsulfanyl)acetylamino]alkanoates
por: El Rayes, Samir Mohamed, et al.
Publicado: (2022)

Synthesis of nanoscale CuO via precursor method and its application in the catalytic epoxidation of styrene
por: Bepari, Ruhul Amin, et al.
Publicado: (2022)

Microwave-Assisted Synthesis of Quinazolines and Quinazolinones: An Overview
por: Mohammadkhani, Leyla, et al.
Publicado: (2020)

Recent advances and prospects in the organocatalytic synthesis of quinazolinones
por: Borah, Biplob, et al.
Publicado: (2022)

Metal-Free Direct C–H Functionalization of Quinoxalin-2(1H)-Ones to Produce 3-Vinylated Quinoxalin-2(1H)-Ones in the Presence of Alkenes
por: Ding, Rongcai, et al.
Publicado: (2021)

α-Hydroxy acid as an aldehyde surrogate: metal-free synthesis of pyrrolo[1,2-a]quinoxalines, quinazolinones, and other N-heterocycles via decarboxylative oxidative annulation reaction
por: Viji, Mayavan, et al.
Publicado: (2020)

Uses of 2-Ethoxy-4(3H) quinazolinone in Synthesis of Quinazoline and Quinazolinone Derivatives of Antimicrobial Activity: The Solvent Effect
por: El-Hashash, Maher A., et al.
Publicado: (2012)

Synthesis and anticancer activity of novel quinazolinone-based rhodanines
por: El-Sayed, Sherihan, et al.
Publicado: (2017)

Enantioselective Copper‐Catalyzed Borylative Cyclization for the Synthesis of Quinazolinones
por: Dherbassy, Quentin, et al.
Publicado: (2021)

A Bifurcated Multicomponent Synthesis Approach to Polycyclic Quinazolinones
por: Xu, Ruixue, et al.
Publicado: (2022)

Synthesis of Novel Quinazolinone Analogues for Quorum Sensing Inhibition
por: Shandil, Sahil, et al.
Publicado: (2023)

“On-Water” Synthesis of Quinazolinones and Dihydroquinazolinones Starting from o-Bromobenzonitrile
por: Liu, Zibin, et al.
Publicado: (2018)

Convenient Synthesis and Anticancer Activity of Methyl 2-[3-(3-Phenyl-quinoxalin-2-ylsulfanyl)propanamido]alkanoates and N-Alkyl 3-((3-Phenyl-quinoxalin-2-yl)sulfanyl)propanamides
por: El Rayes, Samir M., et al.
Publicado: (2019)

Synthesis of Some New Quinazolinone Derivatives and Evaluation of Their Antimicrobial Activities
por: Khodarahmi, Ghadamali, et al.
Publicado: (2012)

Synthesis, Characterization, and Anti-Inflammatory Activity of Newer Quinazolinone Analogs
por: Rajput, Chatrasal Singh, et al.
Publicado: (2013)

New Isoxazolidine-Conjugates of Quinazolinones—Synthesis, Antiviral and Cytostatic Activity
por: Piotrowska, Dorota G., et al.
Publicado: (2016)

Synthesis and cytotoxic evaluation of some derivatives of triazole-quinazolinone hybrids
por: Hassanzadeh, Farshid, et al.
Publicado: (2019)

Synthesis and antimicrobial activity of novel quinazolinone–thiazolidine–quinoline compounds
por: Desai, N.C., et al.
Publicado: (2013)

Synthesis and hypoglycemic activity of quinoxaline derivatives
por: Jia, Weidong, et al.
Publicado: (2023)

Synthesis of some new tricyclic 4(3H)-quinazolinone derivatives
por: Jafari, E., et al.
Publicado: (2011)

Synthesis and antimalarial evaluation of some 4-quinazolinone derivatives based on febrifugine
por: Sen, Debanjan, et al.
Publicado: (2010)

Synthesis and cytotoxic evaluation of novel quinazolinone derivatives as potential anticancer agents
por: Poorirani, Safoora, et al.
Publicado: (2018)

Synthesis of New Proteomimetic Quinazolinone Alkaloids and Evaluation of Their Neuroprotective and Antitumor Effects
por: Long, Solida, et al.
Publicado: (2019)

Synthesis, molecular docking, and cytotoxicity of quinazolinone and dihydroquinazolinone derivatives as cytotoxic agents
por: Taayoshi, Fahimeh, et al.
Publicado: (2022)

Unexpected assembly machinery for 4(3H)-quinazolinone scaffold synthesis
por: Chen, Xi-Wei, et al.
Publicado: (2022)

DNA adducts of propylene oxide and acrylonitrile epoxide: hydrolytic deamination of 3-alkyl-dCyd to 3-alkyl-dUrd.
por: Solomon, J J, et al.
Publicado: (1989)

Synthesis and Properties of Quinoxaline-Containing Benzoxazines and Polybenzoxazines
por: Chen, Chien Han, et al.
Publicado: (2019)

Synthesis of novel antibacterial and antifungal quinoxaline derivatives
por: Tang, Xuemei, et al.
Publicado: (2022)

Electrochemical synthesis of quinazolinone via I(2)-catalyzed tandem oxidation in aqueous solution
por: Hou, Huiqing, et al.
Publicado: (2021)

Newly Designed Quinazolinone Derivatives as Novel Tyrosinase Inhibitor: Synthesis, Inhibitory Activity, and Mechanism
por: Huang, Yaru, et al.
Publicado: (2022)

Visible Light Promotes Cascade Trifluoromethylation/Cyclization, Leading to Trifluoromethylated Polycyclic Quinazolinones, Benzimidazoles and Indoles
por: Ma, Ransong, et al.
Publicado: (2022)

PIDA-mediated intramolecular oxidative C–N bond formation for the direct synthesis of quinoxalines from enaminones
por: Zhang, Hong, et al.
Publicado: (2019)

Quinazolinones, the Winning Horse in Drug Discovery
por: Alsibaee, Aishah M., et al.
Publicado: (2023)

Synthesis of New Furothiazolo Pyrimido Quinazolinones from Visnagenone or Khellinone and Antimicrobial Activity
por: Abu-Hashem, Ameen Ali
Publicado: (2018)

Basic ionic liquid as catalyst and surfactant: green synthesis of quinazolinone in aqueous media
por: Zhang, Yaping, et al.
Publicado: (2018)

Design and synthesis of novel quinazolinone-based derivatives as EGFR inhibitors with antitumor activity
por: Sonousi, Amr, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_f787o1i4ojlq6t898m4jbmavqd