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The Proinflammatory Role of ANGPTL8 R59W Variant in Modulating Inflammation through NF-κB Signaling Pathway under TNFα Stimulation

Background: Angiopoietin-like protein 8 (ANGPTL8) is known to regulate lipid metabolism and inflammation. It interacts with ANGPTL3 and ANGPTL4 to regulate lipoprotein lipase (LPL) activity and with IKK to modulate NF-κB activity. Further, a single nucleotide polymorphism (SNP) leading to the ANGPTL...

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Detalles Bibliográficos
Autores principales:	Abu-Farha, Mohamed, Madhu, Dhanya, Hebbar, Prashantha, Mohammad, Anwar, Channanath, Arshad, Kavalakatt, Sina, Alam-Eldin, Nada, Alterki, Fatima, Taher, Ibrahim, Alsmadi, Osama, Shehab, Mohammad, Arefanian, Hossein, Ahmad, Rasheed, Thanaraj, Thangavel Alphonse, Al-Mulla, Fahd, Abubaker, Jehad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10648545/ https://www.ncbi.nlm.nih.gov/pubmed/37947641 http://dx.doi.org/10.3390/cells12212563

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