Principal Component Analysis of Alternative Splicing Profiles Revealed by Long-Read ONT Sequencing in Human Liver Tissue and Hepatocyte-Derived HepG2 and Huh7 Cell Lines

The long-read RNA sequencing developed by Oxford Nanopore Technology provides a direct quantification of transcript isoforms. That makes the number of transcript isoforms per gene an intrinsically suitable metric for alternative splicing (AS) profiling in the application to this particular type of R...

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Detalles Bibliográficos
Autores principales: Sarygina, Elizaveta, Kozlova, Anna, Deinichenko, Kseniia, Radko, Sergey, Ptitsyn, Konstantin, Khmeleva, Svetlana, Kurbatov, Leonid K., Spirin, Pavel, Prassolov, Vladimir S., Ilgisonis, Ekaterina, Lisitsa, Andrey, Ponomarenko, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10648607/
https://www.ncbi.nlm.nih.gov/pubmed/37958484
http://dx.doi.org/10.3390/ijms242115502

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