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Exploring the Reciprocal Relationship between Depressive Symptoms and Cognitive Function among Chinese Older Adults

(1) Objectives: This study aims to investigate the bidirectional relationship between depressive symptoms and cognitive function among older adults in China, addressing a research gap in the context of developing nations. (2) Methods: A total of 3813 adults aged 60 and older participating in 2013, 2...

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Autores principales: Lu, Jiehua, Ruan, Yunchen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10648665/
https://www.ncbi.nlm.nih.gov/pubmed/37958024
http://dx.doi.org/10.3390/healthcare11212880
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author Lu, Jiehua
Ruan, Yunchen
author_facet Lu, Jiehua
Ruan, Yunchen
author_sort Lu, Jiehua
collection PubMed
description (1) Objectives: This study aims to investigate the bidirectional relationship between depressive symptoms and cognitive function among older adults in China, addressing a research gap in the context of developing nations. (2) Methods: A total of 3813 adults aged 60 and older participating in 2013, 2015, and 2018 waves of the China Health and Retirement Longitudinal Study (CHARLS) were included. A fixed-effects model and cross-lagged panel model (CLPM) was utilized. (3) Results: First, the results indicated that a significant negative correlation existed between depressive symptoms and cognitive function in older adults during the study period (β = −0.084, p < 0.001). Second, after controlling for unobserved confounding factors, the deterioration and improvement of depressive symptoms still significantly affected cognitive function (β = −0.055, p < 0.001). Third, using the cross-lagged panel model, we observed a reciprocal relationship between depressive symptoms (Dep) and cognitive function (Cog) among Chinese older adults (Dep2013 → Cog2015, β = −0.025, p < 0.01; Dep2015 → Cog2018, β = −0.028, p < 0.001; Cog2013 → Dep2015, β = −0.079, p < 0.01; Cog2015 → Dep2018, β = −0.085, p < 0.01). (4) Discussion: The reciprocal relationship between depressive symptoms and cognitive functioning in older adults emphasizes the need for integrated public health policies and clinical interventions, to develop comprehensive intervention strategies that simultaneously address depressive symptoms and cognitive decline.
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spelling pubmed-106486652023-11-01 Exploring the Reciprocal Relationship between Depressive Symptoms and Cognitive Function among Chinese Older Adults Lu, Jiehua Ruan, Yunchen Healthcare (Basel) Article (1) Objectives: This study aims to investigate the bidirectional relationship between depressive symptoms and cognitive function among older adults in China, addressing a research gap in the context of developing nations. (2) Methods: A total of 3813 adults aged 60 and older participating in 2013, 2015, and 2018 waves of the China Health and Retirement Longitudinal Study (CHARLS) were included. A fixed-effects model and cross-lagged panel model (CLPM) was utilized. (3) Results: First, the results indicated that a significant negative correlation existed between depressive symptoms and cognitive function in older adults during the study period (β = −0.084, p < 0.001). Second, after controlling for unobserved confounding factors, the deterioration and improvement of depressive symptoms still significantly affected cognitive function (β = −0.055, p < 0.001). Third, using the cross-lagged panel model, we observed a reciprocal relationship between depressive symptoms (Dep) and cognitive function (Cog) among Chinese older adults (Dep2013 → Cog2015, β = −0.025, p < 0.01; Dep2015 → Cog2018, β = −0.028, p < 0.001; Cog2013 → Dep2015, β = −0.079, p < 0.01; Cog2015 → Dep2018, β = −0.085, p < 0.01). (4) Discussion: The reciprocal relationship between depressive symptoms and cognitive functioning in older adults emphasizes the need for integrated public health policies and clinical interventions, to develop comprehensive intervention strategies that simultaneously address depressive symptoms and cognitive decline. MDPI 2023-11-01 /pmc/articles/PMC10648665/ /pubmed/37958024 http://dx.doi.org/10.3390/healthcare11212880 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lu, Jiehua
Ruan, Yunchen
Exploring the Reciprocal Relationship between Depressive Symptoms and Cognitive Function among Chinese Older Adults
title Exploring the Reciprocal Relationship between Depressive Symptoms and Cognitive Function among Chinese Older Adults
title_full Exploring the Reciprocal Relationship between Depressive Symptoms and Cognitive Function among Chinese Older Adults
title_fullStr Exploring the Reciprocal Relationship between Depressive Symptoms and Cognitive Function among Chinese Older Adults
title_full_unstemmed Exploring the Reciprocal Relationship between Depressive Symptoms and Cognitive Function among Chinese Older Adults
title_short Exploring the Reciprocal Relationship between Depressive Symptoms and Cognitive Function among Chinese Older Adults
title_sort exploring the reciprocal relationship between depressive symptoms and cognitive function among chinese older adults
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10648665/
https://www.ncbi.nlm.nih.gov/pubmed/37958024
http://dx.doi.org/10.3390/healthcare11212880
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