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Short-term outcomes following total correction of tetralogy of fallot in adult patients

OBJECTIVES: Tetralogy of Fallot (TOF) is a common congenital heart disease which should be corrected. The recommended time for the Tetralogy of Fallot Total Correction (TFTC) surgery is during the infancy for the possible difficulties during the surgery and the related issues. However, sometimes TOF...

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Autores principales: Khajali, Zahra, Mohammadi, Nasibeh, Toloueitabar, Yaser, Maleki, Majid, Saedi, Sedigheh, Norouzi, Zeinab, Mazloum-Zadeh, Saeedeh, Chenaghlou, Maryam, Jalali, Amirhossein, Tatari, Hassan, Aliramezany, Maryam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10648666/
https://www.ncbi.nlm.nih.gov/pubmed/37964350
http://dx.doi.org/10.1186/s13019-023-02411-1
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author Khajali, Zahra
Mohammadi, Nasibeh
Toloueitabar, Yaser
Maleki, Majid
Saedi, Sedigheh
Norouzi, Zeinab
Mazloum-Zadeh, Saeedeh
Chenaghlou, Maryam
Jalali, Amirhossein
Tatari, Hassan
Aliramezany, Maryam
author_facet Khajali, Zahra
Mohammadi, Nasibeh
Toloueitabar, Yaser
Maleki, Majid
Saedi, Sedigheh
Norouzi, Zeinab
Mazloum-Zadeh, Saeedeh
Chenaghlou, Maryam
Jalali, Amirhossein
Tatari, Hassan
Aliramezany, Maryam
author_sort Khajali, Zahra
collection PubMed
description OBJECTIVES: Tetralogy of Fallot (TOF) is a common congenital heart disease which should be corrected. The recommended time for the Tetralogy of Fallot Total Correction (TFTC) surgery is during the infancy for the possible difficulties during the surgery and the related issues. However, sometimes TOF is diagnosed and managed during the adulthood. METHODS: This study is a descriptive and retrospective one which included all patients who underwent TFTC at the age of 15-year and older in 10 years (between the years 2010 and 2020) to identify short-term (in-hospital mortality, ICU stay, postoperative bleeding, respiratory complications after the surgery such as pulmonary edema, pneumonia, etc.) and one-year (left ventricle ejection fraction (LVEF), right ventricle (RV) ejection fraction, the severity of tricuspid and aortic regurgitation after surgery) outcomes. All data were taken from medical records at Rajaie Cardiovascular Medical and Research Center. Data were analyzed using SPSS 22. RESULTS: 94 patients with the mean ± SD age of 26.7 ± 9.6 years were enrolled. Most of them were male (59.6%) (P-value: 0.009). In-hospital mortality in our study were 5.3%. Tricuspid regurgitation (TR) was significantly resolved after the surgery (P-value: 0.006). Of 17 (18.1%) patients with small or hypoplastic pulmonary artery (PA) branches, 14 patients had acceptable PA branch size after surgery. CONCLUSION: TFTC at an older age is safe with acceptable results. Age is not a contraindication for TFTC and surgery should be recommended if the patients are diagnosed with TOF in adulthood. Also, the TOF diagnosis should be considered in adult patients with suspicious signs and symptoms.
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spelling pubmed-106486662023-11-14 Short-term outcomes following total correction of tetralogy of fallot in adult patients Khajali, Zahra Mohammadi, Nasibeh Toloueitabar, Yaser Maleki, Majid Saedi, Sedigheh Norouzi, Zeinab Mazloum-Zadeh, Saeedeh Chenaghlou, Maryam Jalali, Amirhossein Tatari, Hassan Aliramezany, Maryam J Cardiothorac Surg Research OBJECTIVES: Tetralogy of Fallot (TOF) is a common congenital heart disease which should be corrected. The recommended time for the Tetralogy of Fallot Total Correction (TFTC) surgery is during the infancy for the possible difficulties during the surgery and the related issues. However, sometimes TOF is diagnosed and managed during the adulthood. METHODS: This study is a descriptive and retrospective one which included all patients who underwent TFTC at the age of 15-year and older in 10 years (between the years 2010 and 2020) to identify short-term (in-hospital mortality, ICU stay, postoperative bleeding, respiratory complications after the surgery such as pulmonary edema, pneumonia, etc.) and one-year (left ventricle ejection fraction (LVEF), right ventricle (RV) ejection fraction, the severity of tricuspid and aortic regurgitation after surgery) outcomes. All data were taken from medical records at Rajaie Cardiovascular Medical and Research Center. Data were analyzed using SPSS 22. RESULTS: 94 patients with the mean ± SD age of 26.7 ± 9.6 years were enrolled. Most of them were male (59.6%) (P-value: 0.009). In-hospital mortality in our study were 5.3%. Tricuspid regurgitation (TR) was significantly resolved after the surgery (P-value: 0.006). Of 17 (18.1%) patients with small or hypoplastic pulmonary artery (PA) branches, 14 patients had acceptable PA branch size after surgery. CONCLUSION: TFTC at an older age is safe with acceptable results. Age is not a contraindication for TFTC and surgery should be recommended if the patients are diagnosed with TOF in adulthood. Also, the TOF diagnosis should be considered in adult patients with suspicious signs and symptoms. BioMed Central 2023-11-14 /pmc/articles/PMC10648666/ /pubmed/37964350 http://dx.doi.org/10.1186/s13019-023-02411-1 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Khajali, Zahra
Mohammadi, Nasibeh
Toloueitabar, Yaser
Maleki, Majid
Saedi, Sedigheh
Norouzi, Zeinab
Mazloum-Zadeh, Saeedeh
Chenaghlou, Maryam
Jalali, Amirhossein
Tatari, Hassan
Aliramezany, Maryam
Short-term outcomes following total correction of tetralogy of fallot in adult patients
title Short-term outcomes following total correction of tetralogy of fallot in adult patients
title_full Short-term outcomes following total correction of tetralogy of fallot in adult patients
title_fullStr Short-term outcomes following total correction of tetralogy of fallot in adult patients
title_full_unstemmed Short-term outcomes following total correction of tetralogy of fallot in adult patients
title_short Short-term outcomes following total correction of tetralogy of fallot in adult patients
title_sort short-term outcomes following total correction of tetralogy of fallot in adult patients
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10648666/
https://www.ncbi.nlm.nih.gov/pubmed/37964350
http://dx.doi.org/10.1186/s13019-023-02411-1
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