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Ethnobotanical, Phytochemical, and Pharmacological Properties of the Subfamily Nepetoideae (Lamiaceae) in Inflammatory Diseases

Nepetoideae is the most diverse subfamily of Lamiaceae, and some species are well known for their culinary and medicinal uses. In recent years, there has been growing interest in the therapeutic properties of the species of this group regarding inflammatory illnesses. This study aims to collect info...

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Autores principales: Ortiz-Mendoza, Nancy, Martínez-Gordillo, Martha Juana, Martínez-Ambriz, Emmanuel, Basurto-Peña, Francisco Alberto, González-Trujano, María Eva, Aguirre-Hernández, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10648697/
https://www.ncbi.nlm.nih.gov/pubmed/37960108
http://dx.doi.org/10.3390/plants12213752
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author Ortiz-Mendoza, Nancy
Martínez-Gordillo, Martha Juana
Martínez-Ambriz, Emmanuel
Basurto-Peña, Francisco Alberto
González-Trujano, María Eva
Aguirre-Hernández, Eva
author_facet Ortiz-Mendoza, Nancy
Martínez-Gordillo, Martha Juana
Martínez-Ambriz, Emmanuel
Basurto-Peña, Francisco Alberto
González-Trujano, María Eva
Aguirre-Hernández, Eva
author_sort Ortiz-Mendoza, Nancy
collection PubMed
description Nepetoideae is the most diverse subfamily of Lamiaceae, and some species are well known for their culinary and medicinal uses. In recent years, there has been growing interest in the therapeutic properties of the species of this group regarding inflammatory illnesses. This study aims to collect information on traditional uses through ethnobotanical, pharmacological, and phytochemical information of the subfamily Nepetoideae related to inflammatory diseases. UNAM electronic resources were used to obtain the information. The analysis of the most relevant literature was compiled and organised in tables. From this, about 106 species of the subfamily are traditionally recognised to alleviate chronic pain associated with inflammation. Pharmacological studies have been carried out in vitro and in vivo on approximately 308 species belonging to the genera Salvia, Ocimum, Thymus, Mentha, Origanum, Lavandula, and Melissa. Phytochemical and pharmacological evaluations have been performed and mostly prepared as essential oil or high polarity extracts, whose secondary metabolites are mainly of a phenolic nature. Other interesting and explored metabolites are diterpenes from the abietane, clerodane, and kaurane type; however, they have only been described in some species of the genera Salvia and Isodon. This review reveals that the Nepetoideae subfamily is an important source for therapeutics of the inflammatory process.
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spelling pubmed-106486972023-11-02 Ethnobotanical, Phytochemical, and Pharmacological Properties of the Subfamily Nepetoideae (Lamiaceae) in Inflammatory Diseases Ortiz-Mendoza, Nancy Martínez-Gordillo, Martha Juana Martínez-Ambriz, Emmanuel Basurto-Peña, Francisco Alberto González-Trujano, María Eva Aguirre-Hernández, Eva Plants (Basel) Review Nepetoideae is the most diverse subfamily of Lamiaceae, and some species are well known for their culinary and medicinal uses. In recent years, there has been growing interest in the therapeutic properties of the species of this group regarding inflammatory illnesses. This study aims to collect information on traditional uses through ethnobotanical, pharmacological, and phytochemical information of the subfamily Nepetoideae related to inflammatory diseases. UNAM electronic resources were used to obtain the information. The analysis of the most relevant literature was compiled and organised in tables. From this, about 106 species of the subfamily are traditionally recognised to alleviate chronic pain associated with inflammation. Pharmacological studies have been carried out in vitro and in vivo on approximately 308 species belonging to the genera Salvia, Ocimum, Thymus, Mentha, Origanum, Lavandula, and Melissa. Phytochemical and pharmacological evaluations have been performed and mostly prepared as essential oil or high polarity extracts, whose secondary metabolites are mainly of a phenolic nature. Other interesting and explored metabolites are diterpenes from the abietane, clerodane, and kaurane type; however, they have only been described in some species of the genera Salvia and Isodon. This review reveals that the Nepetoideae subfamily is an important source for therapeutics of the inflammatory process. MDPI 2023-11-02 /pmc/articles/PMC10648697/ /pubmed/37960108 http://dx.doi.org/10.3390/plants12213752 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ortiz-Mendoza, Nancy
Martínez-Gordillo, Martha Juana
Martínez-Ambriz, Emmanuel
Basurto-Peña, Francisco Alberto
González-Trujano, María Eva
Aguirre-Hernández, Eva
Ethnobotanical, Phytochemical, and Pharmacological Properties of the Subfamily Nepetoideae (Lamiaceae) in Inflammatory Diseases
title Ethnobotanical, Phytochemical, and Pharmacological Properties of the Subfamily Nepetoideae (Lamiaceae) in Inflammatory Diseases
title_full Ethnobotanical, Phytochemical, and Pharmacological Properties of the Subfamily Nepetoideae (Lamiaceae) in Inflammatory Diseases
title_fullStr Ethnobotanical, Phytochemical, and Pharmacological Properties of the Subfamily Nepetoideae (Lamiaceae) in Inflammatory Diseases
title_full_unstemmed Ethnobotanical, Phytochemical, and Pharmacological Properties of the Subfamily Nepetoideae (Lamiaceae) in Inflammatory Diseases
title_short Ethnobotanical, Phytochemical, and Pharmacological Properties of the Subfamily Nepetoideae (Lamiaceae) in Inflammatory Diseases
title_sort ethnobotanical, phytochemical, and pharmacological properties of the subfamily nepetoideae (lamiaceae) in inflammatory diseases
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10648697/
https://www.ncbi.nlm.nih.gov/pubmed/37960108
http://dx.doi.org/10.3390/plants12213752
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