Interleukin-7 deficiency in rheumatoid arthritis: consequences for therapy-induced lymphopenia

We previously demonstrated prolonged, profound CD4(+ )T-lymphopenia in rheumatoid arthritis (RA) patients following lymphocyte-depleting therapy. Poor reconstitution could result either from reduced de novo T-cell production through the thymus or from poor peripheral expansion of residual T-cells. I...

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Detalles Bibliográficos
Autores principales: Ponchel, Frederique, Verburg, Robert J, Bingham, Sarah J, Brown, Andrew K, Moore, John, Protheroe, Andrew, Short, Kath, Lawson, Catherine A, Morgan, Ann W, Quinn, Mark, Buch, Maya, Field, Sarah L, Maltby, Sarah L, Masurel, Aurelie, Douglas, Susan H, Straszynski, Liz, Fearon, Ursula, Veale, Douglas J, Patel, Poulam, McGonagle, Dennis, Snowden, John, Markham, Alexander F, Ma, David, van Laar, Jacob M, Papadaki, Helen A, Emery, Paul, Isaacs, John D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1064881/
https://www.ncbi.nlm.nih.gov/pubmed/15642146
http://dx.doi.org/10.1186/ar1452

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