Switching Rat Resident Macrophages from M1 to M2 Phenotype by Iba1 Silencing Has Analgesic Effects in SNL-Induced Neuropathic Pain

Resident macrophages from dorsal root ganglia are important for the development of traumatic-induced neuropathic pain. In the first 5–7 days after a traumatic sciatic nerve injury (i.e., spinal nerve ligation (SNL), spared nerve injury (SNI), sciatic nerve transection or sciatic nerve ligation and t...

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Detalles Bibliográficos
Autores principales: Gheorghe, Roxana-Olimpia, Grosu, Andreea Violeta, Magercu, Melania, Ghenghea, Mihail-Sebastian, Zbarcea, Cristina Elena, Tanase, Alexandra, Negres, Simona, Filippi, Alexandru, Chiritoiu, Gabriela, Gherghiceanu, Mihaela, Dinescu, Sorina, Gaina, Gisela, Sapunar, Damir, Ristoiu, Violeta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10648812/
https://www.ncbi.nlm.nih.gov/pubmed/37958812
http://dx.doi.org/10.3390/ijms242115831

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