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MMP-3 expression and release by rheumatoid arthritis fibroblast-like synoviocytes induced with a bacterial ligand of integrin α5β1
Fibroblast-like synoviocytes (FLSs) play a major role in the pathogenesis of rheumatoid arthritis (RA) by secreting effector molecules that promote inflammation and joint destruction. How these cells become and remain activated is still elusive. Both genetic and environmental factors probably play a...
Autores principales: | Zeisel, Mirjam B, Druet, Vanessa A, Wachsmann, Dominique, Sibilia, Jean |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1064889/ https://www.ncbi.nlm.nih.gov/pubmed/15642131 http://dx.doi.org/10.1186/ar1462 |
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