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MMP-3 expression and release by rheumatoid arthritis fibroblast-like synoviocytes induced with a bacterial ligand of integrin α5β1

Fibroblast-like synoviocytes (FLSs) play a major role in the pathogenesis of rheumatoid arthritis (RA) by secreting effector molecules that promote inflammation and joint destruction. How these cells become and remain activated is still elusive. Both genetic and environmental factors probably play a...

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Detalles Bibliográficos
Autores principales: Zeisel, Mirjam B, Druet, Vanessa A, Wachsmann, Dominique, Sibilia, Jean
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1064889/
https://www.ncbi.nlm.nih.gov/pubmed/15642131
http://dx.doi.org/10.1186/ar1462

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