Simplified urine-based method to detect rifampin underexposure in adults with tuberculosis: a prospective diagnostic accuracy study

Variable pharmacokinetics of rifampin in tuberculosis (TB) treatment can lead to poor outcomes. Urine spectrophotometry is simpler and more accessible than recommended serum-based drug monitoring, but its optimal efficacy in predicting serum rifampin underexposure in adults with TB remains uncertain...

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Detalles Bibliográficos
Autores principales: Xie, Yingda L., Modi, Nisha, Handler, Deborah, Yu, Sijia, Rao, Prakruti, Kagan, Leonid, Petros de Guex, Kristen, Reiss, Robert, Siemiątkowska, Anna, Narang, Anshika, Narayanan, Navaneeth, Hearn, Jasie, Khalil, Amanda, Woods, Patricia, Young, Laura, Lardizabal, Alfred, Subbian, Selvakumar, Peloquin, Charles A., Vinnard, Christopher, Thomas, Tania A., Heysell, Scott K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10648923/
https://www.ncbi.nlm.nih.gov/pubmed/37877727
http://dx.doi.org/10.1128/aac.00932-23

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