Safety and pharmacokinetics of SPR206 in subjects with varying degrees of renal impairment

SPR206 is a novel polymyxin derivative with potent in vitro activity against susceptible and multidrug-resistant strains of Acinetobacter baumannii, Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli, and Enterobacter species. SPR206 is eliminated renally. The safety, tolerability, and...

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Detalles Bibliográficos
Autores principales: Bruss, Jon B., Bader, Justin, Hamed, Kamal A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10648942/
https://www.ncbi.nlm.nih.gov/pubmed/37823647
http://dx.doi.org/10.1128/aac.00505-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10648942/
https://www.ncbi.nlm.nih.gov/pubmed/37823647
http://dx.doi.org/10.1128/aac.00505-23

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