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Differentiating Dyes: A Spectroscopic Investigation into the Composition of Scarlet Bloodroot (Haemodorum coccineum R.Br.) Rhizome

Haemodorum coccineum, commonly known as scarlet bloodroot, is a plant native to New Guinea and the northern most parts of Australia. The highly coloured H. coccineum is used by communities in Larrakia country for dyeing garments and occasionally to treat snake bites. Previous studies into H. coccine...

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Autores principales: Carpinelli de Jesus, Matheus, Church, Taylah, Wapling, Johanna A., Collins, Raelene, Leach, Gregory J., Leach, David, De Voss, James J., Blanchfield, Joanne T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10648959/
https://www.ncbi.nlm.nih.gov/pubmed/37959841
http://dx.doi.org/10.3390/molecules28217422
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author Carpinelli de Jesus, Matheus
Church, Taylah
Wapling, Johanna A.
Collins, Raelene
Leach, Gregory J.
Leach, David
De Voss, James J.
Blanchfield, Joanne T.
author_facet Carpinelli de Jesus, Matheus
Church, Taylah
Wapling, Johanna A.
Collins, Raelene
Leach, Gregory J.
Leach, David
De Voss, James J.
Blanchfield, Joanne T.
author_sort Carpinelli de Jesus, Matheus
collection PubMed
description Haemodorum coccineum, commonly known as scarlet bloodroot, is a plant native to New Guinea and the northern most parts of Australia. The highly coloured H. coccineum is used by communities in Larrakia country for dyeing garments and occasionally to treat snake bites. Previous studies into H. coccineum have focused on its taxonomic classification, with this being the first evaluation of the chemical composition of the plant. Haemodoraceae plants are reported to contain phenylphenalenones (PhPs), which are highly conjugated polycyclic oxygenated aromatic hydrocarbons. We report the characterisation of 20 compounds extracted from the rhizome of H. coccineum: four sugars and 16 compounds belonging to the PhP family. The compounds include five aglycones and seven glycosylated compounds, of which four contain malonate esters in their structures. Characterisation of these compounds was achieved through 1D and 2D NMR, MS analysis and comparison to the known phytochemistry of other species from the Haemodorum genus. Preliminary anti-microbial activity of the crude extract shows significant inhibition of the growth of both gram-positive and gram-negative bacteria, but no activity against Candida albicans.
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spelling pubmed-106489592023-11-03 Differentiating Dyes: A Spectroscopic Investigation into the Composition of Scarlet Bloodroot (Haemodorum coccineum R.Br.) Rhizome Carpinelli de Jesus, Matheus Church, Taylah Wapling, Johanna A. Collins, Raelene Leach, Gregory J. Leach, David De Voss, James J. Blanchfield, Joanne T. Molecules Article Haemodorum coccineum, commonly known as scarlet bloodroot, is a plant native to New Guinea and the northern most parts of Australia. The highly coloured H. coccineum is used by communities in Larrakia country for dyeing garments and occasionally to treat snake bites. Previous studies into H. coccineum have focused on its taxonomic classification, with this being the first evaluation of the chemical composition of the plant. Haemodoraceae plants are reported to contain phenylphenalenones (PhPs), which are highly conjugated polycyclic oxygenated aromatic hydrocarbons. We report the characterisation of 20 compounds extracted from the rhizome of H. coccineum: four sugars and 16 compounds belonging to the PhP family. The compounds include five aglycones and seven glycosylated compounds, of which four contain malonate esters in their structures. Characterisation of these compounds was achieved through 1D and 2D NMR, MS analysis and comparison to the known phytochemistry of other species from the Haemodorum genus. Preliminary anti-microbial activity of the crude extract shows significant inhibition of the growth of both gram-positive and gram-negative bacteria, but no activity against Candida albicans. MDPI 2023-11-03 /pmc/articles/PMC10648959/ /pubmed/37959841 http://dx.doi.org/10.3390/molecules28217422 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Carpinelli de Jesus, Matheus
Church, Taylah
Wapling, Johanna A.
Collins, Raelene
Leach, Gregory J.
Leach, David
De Voss, James J.
Blanchfield, Joanne T.
Differentiating Dyes: A Spectroscopic Investigation into the Composition of Scarlet Bloodroot (Haemodorum coccineum R.Br.) Rhizome
title Differentiating Dyes: A Spectroscopic Investigation into the Composition of Scarlet Bloodroot (Haemodorum coccineum R.Br.) Rhizome
title_full Differentiating Dyes: A Spectroscopic Investigation into the Composition of Scarlet Bloodroot (Haemodorum coccineum R.Br.) Rhizome
title_fullStr Differentiating Dyes: A Spectroscopic Investigation into the Composition of Scarlet Bloodroot (Haemodorum coccineum R.Br.) Rhizome
title_full_unstemmed Differentiating Dyes: A Spectroscopic Investigation into the Composition of Scarlet Bloodroot (Haemodorum coccineum R.Br.) Rhizome
title_short Differentiating Dyes: A Spectroscopic Investigation into the Composition of Scarlet Bloodroot (Haemodorum coccineum R.Br.) Rhizome
title_sort differentiating dyes: a spectroscopic investigation into the composition of scarlet bloodroot (haemodorum coccineum r.br.) rhizome
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10648959/
https://www.ncbi.nlm.nih.gov/pubmed/37959841
http://dx.doi.org/10.3390/molecules28217422
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