NLRP3 Inflammasome Activates Endothelial-to-Mesenchymal Transition via Focal Adhesion Kinase Pathway in Bleomycin-Induced Pulmonary Fibrosis

Idiopathic pulmonary fibrosis has poor clinical outcomes despite antifibrotic treatment. The nucleotide-binding domain leucine-rich repeat-containing receptor, pyrin domain-containing-3 (NLRP3) inflammasome and endothelial-to-mesenchymal transition (EndoMT) were shown to be involved in the pathogene...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Wei-Chih, Yu, Wen-Kuang, Su, Vincent Yi-Fong, Hsu, Han-Shui, Yang, Kuang-Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10648980/
https://www.ncbi.nlm.nih.gov/pubmed/37958797
http://dx.doi.org/10.3390/ijms242115813

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10648980/
https://www.ncbi.nlm.nih.gov/pubmed/37958797
http://dx.doi.org/10.3390/ijms242115813

Ejemplares similares