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NLRP3 Inflammasome Activates Endothelial-to-Mesenchymal Transition via Focal Adhesion Kinase Pathway in Bleomycin-Induced Pulmonary Fibrosis

Idiopathic pulmonary fibrosis has poor clinical outcomes despite antifibrotic treatment. The nucleotide-binding domain leucine-rich repeat-containing receptor, pyrin domain-containing-3 (NLRP3) inflammasome and endothelial-to-mesenchymal transition (EndoMT) were shown to be involved in the pathogene...

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Detalles Bibliográficos
Autores principales:	Chen, Wei-Chih, Yu, Wen-Kuang, Su, Vincent Yi-Fong, Hsu, Han-Shui, Yang, Kuang-Yao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10648980/ https://www.ncbi.nlm.nih.gov/pubmed/37958797 http://dx.doi.org/10.3390/ijms242115813

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