Cargando…

DAZL Knockout Pigs as Recipients for Spermatogonial Stem Cell Transplantation

Spermatogonial stem cell (SSC) transplantation into the testis of a germ cell (GC)-depleted surrogate allows transmission of donor genotype via donor-derived sperm produced by the recipient. Transplantation of gene-edited SSCs provides an approach to propagate gene-edited large animal models. DAZL i...

Descripción completa

Detalles Bibliográficos
Autores principales: Lara, Nathalia L. M., Goldsmith, Taylor, Rodriguez-Villamil, Paula, Ongaratto, Felipe, Solin, Staci, Webster, Dennis, Ganbaatar, Uyanga, Hodgson, Shane, Corbière, Stanislas M. A. S., Bondareva, Alla, Carlson, Daniel F., Dobrinski, Ina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649044/
https://www.ncbi.nlm.nih.gov/pubmed/37947660
http://dx.doi.org/10.3390/cells12212582