Cargando…
DAZL Knockout Pigs as Recipients for Spermatogonial Stem Cell Transplantation
Spermatogonial stem cell (SSC) transplantation into the testis of a germ cell (GC)-depleted surrogate allows transmission of donor genotype via donor-derived sperm produced by the recipient. Transplantation of gene-edited SSCs provides an approach to propagate gene-edited large animal models. DAZL i...
Autores principales: | Lara, Nathalia L. M., Goldsmith, Taylor, Rodriguez-Villamil, Paula, Ongaratto, Felipe, Solin, Staci, Webster, Dennis, Ganbaatar, Uyanga, Hodgson, Shane, Corbière, Stanislas M. A. S., Bondareva, Alla, Carlson, Daniel F., Dobrinski, Ina |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649044/ https://www.ncbi.nlm.nih.gov/pubmed/37947660 http://dx.doi.org/10.3390/cells12212582 |
Ejemplares similares
-
Targeted Gene Editing in Porcine Spermatogonia
por: Webster, Dennis, et al.
Publicado: (2021) -
Metabolic Requirements for Spermatogonial Stem Cell Establishment and Maintenance In Vivo and In Vitro
por: Voigt, Anna Laura, et al.
Publicado: (2021) -
DAZL mediates a broad translational program regulating expansion and differentiation of spermatogonial progenitors
por: Mikedis, Maria M, et al.
Publicado: (2020) -
CRISPR/Cas9-editing of KISS1 to generate pigs with hypogonadotropic hypogonadism as a castration free trait
por: Flórez, Julio M., et al.
Publicado: (2023) -
A Role for Exchange of Extracellular Vesicles in Porcine Spermatogonial Co-Culture
por: Thiageswaran, Shiama, et al.
Publicado: (2022)