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Optimized Leaky-Wave Antenna for Hyperthermia in Biological Tissue Theoretical Model

In this paper, we exploit the enhanced penetration reachable through inhomogeneous waves to induce hyperthermia in biological tissues. We will present a leaky-wave antenna inspired by the Menzel antenna which has been shortened through opportune design and optimizations and that has been designed to...

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Autores principales: Calcaterra, Alessandro, Simeoni, Patrizio, Migliore, Marco Donald, Mangini, Fabio, Frezza, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649054/
https://www.ncbi.nlm.nih.gov/pubmed/37960621
http://dx.doi.org/10.3390/s23218923
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author Calcaterra, Alessandro
Simeoni, Patrizio
Migliore, Marco Donald
Mangini, Fabio
Frezza, Fabrizio
author_facet Calcaterra, Alessandro
Simeoni, Patrizio
Migliore, Marco Donald
Mangini, Fabio
Frezza, Fabrizio
author_sort Calcaterra, Alessandro
collection PubMed
description In this paper, we exploit the enhanced penetration reachable through inhomogeneous waves to induce hyperthermia in biological tissues. We will present a leaky-wave antenna inspired by the Menzel antenna which has been shortened through opportune design and optimizations and that has been designed to optimize the penetration at the interface with the skin, allowing penetration in the skin layer at a constant temperature, and enhanced penetration in the overall structure considered. Past papers both numerically and analytically demonstrated the possibility of reducing the attenuation that the electromagnetic waves are subject to when travelling inside a lossy medium by using inhomogeneous waves. In those papers, a structure (the leaky-wave antenna) is shown to allow the effect, but such a radiator suffers from low efficiency. Also, at the frequencies that are most used for hyperthermia application, a classical leaky-wave antenna would be too long; here is where the idea of the shortened leaky-wave arises. To numerically analyze the penetration in biological tissues, this paper considers a numerical prototype of a sample of flesh, composed of superficial skin layers, followed by fat and an undefined layer of muscles.
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spelling pubmed-106490542023-11-02 Optimized Leaky-Wave Antenna for Hyperthermia in Biological Tissue Theoretical Model Calcaterra, Alessandro Simeoni, Patrizio Migliore, Marco Donald Mangini, Fabio Frezza, Fabrizio Sensors (Basel) Article In this paper, we exploit the enhanced penetration reachable through inhomogeneous waves to induce hyperthermia in biological tissues. We will present a leaky-wave antenna inspired by the Menzel antenna which has been shortened through opportune design and optimizations and that has been designed to optimize the penetration at the interface with the skin, allowing penetration in the skin layer at a constant temperature, and enhanced penetration in the overall structure considered. Past papers both numerically and analytically demonstrated the possibility of reducing the attenuation that the electromagnetic waves are subject to when travelling inside a lossy medium by using inhomogeneous waves. In those papers, a structure (the leaky-wave antenna) is shown to allow the effect, but such a radiator suffers from low efficiency. Also, at the frequencies that are most used for hyperthermia application, a classical leaky-wave antenna would be too long; here is where the idea of the shortened leaky-wave arises. To numerically analyze the penetration in biological tissues, this paper considers a numerical prototype of a sample of flesh, composed of superficial skin layers, followed by fat and an undefined layer of muscles. MDPI 2023-11-02 /pmc/articles/PMC10649054/ /pubmed/37960621 http://dx.doi.org/10.3390/s23218923 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Calcaterra, Alessandro
Simeoni, Patrizio
Migliore, Marco Donald
Mangini, Fabio
Frezza, Fabrizio
Optimized Leaky-Wave Antenna for Hyperthermia in Biological Tissue Theoretical Model
title Optimized Leaky-Wave Antenna for Hyperthermia in Biological Tissue Theoretical Model
title_full Optimized Leaky-Wave Antenna for Hyperthermia in Biological Tissue Theoretical Model
title_fullStr Optimized Leaky-Wave Antenna for Hyperthermia in Biological Tissue Theoretical Model
title_full_unstemmed Optimized Leaky-Wave Antenna for Hyperthermia in Biological Tissue Theoretical Model
title_short Optimized Leaky-Wave Antenna for Hyperthermia in Biological Tissue Theoretical Model
title_sort optimized leaky-wave antenna for hyperthermia in biological tissue theoretical model
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649054/
https://www.ncbi.nlm.nih.gov/pubmed/37960621
http://dx.doi.org/10.3390/s23218923
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