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Antimicrobial and Antiproliferative Coatings for Stents in Veterinary Medicine—State of the Art and Perspectives
Microbial colonization in veterinary stents poses a significant and concerning issue in veterinary medicine. Over time, these pathogens, particularly bacteria, can colonize the stent surfaces, leading to various complications. Two weeks following the stent insertion procedure, the colonization becom...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649059/ https://www.ncbi.nlm.nih.gov/pubmed/37959431 http://dx.doi.org/10.3390/ma16216834 |
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author | Graczyk, Szymon Pasławski, Robert Grzeczka, Arkadiusz Pasławska, Urszula Świeczko-Żurek, Beata Malisz, Klaudia Popat, Ketul Sionkowska, Alina Golińska, Patrycja Rai, Mahendra |
author_facet | Graczyk, Szymon Pasławski, Robert Grzeczka, Arkadiusz Pasławska, Urszula Świeczko-Żurek, Beata Malisz, Klaudia Popat, Ketul Sionkowska, Alina Golińska, Patrycja Rai, Mahendra |
author_sort | Graczyk, Szymon |
collection | PubMed |
description | Microbial colonization in veterinary stents poses a significant and concerning issue in veterinary medicine. Over time, these pathogens, particularly bacteria, can colonize the stent surfaces, leading to various complications. Two weeks following the stent insertion procedure, the colonization becomes observable, with the aggressiveness of bacterial growth directly correlating with the duration of stent placement. Such microbial colonization can result in infections and inflammations, compromising the stent’s efficacy and, subsequently, the animal patient’s overall well-being. Managing and mitigating the impact of these pathogens on veterinary stents is a crucial challenge that veterinarians and researchers are actively addressing to ensure the successful treatment and recovery of their animal patients. In addition, irritation of the tissue in the form of an inserted stent can lead to overgrowth of granulation tissue, leading to the closure of the stent lumen, as is most often the case in the trachea. Such serious complications after stent placement require improvements in the procedures used to date. In this review, antibacterial or antibiofilm strategies for several stents used in veterinary medicine have been discussed based on the current literature and the perspectives have been drawn. Various coating strategies such as coating with hydrogel, antibiotic, or other antimicrobial agents have been reviewed. |
format | Online Article Text |
id | pubmed-10649059 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-106490592023-10-24 Antimicrobial and Antiproliferative Coatings for Stents in Veterinary Medicine—State of the Art and Perspectives Graczyk, Szymon Pasławski, Robert Grzeczka, Arkadiusz Pasławska, Urszula Świeczko-Żurek, Beata Malisz, Klaudia Popat, Ketul Sionkowska, Alina Golińska, Patrycja Rai, Mahendra Materials (Basel) Review Microbial colonization in veterinary stents poses a significant and concerning issue in veterinary medicine. Over time, these pathogens, particularly bacteria, can colonize the stent surfaces, leading to various complications. Two weeks following the stent insertion procedure, the colonization becomes observable, with the aggressiveness of bacterial growth directly correlating with the duration of stent placement. Such microbial colonization can result in infections and inflammations, compromising the stent’s efficacy and, subsequently, the animal patient’s overall well-being. Managing and mitigating the impact of these pathogens on veterinary stents is a crucial challenge that veterinarians and researchers are actively addressing to ensure the successful treatment and recovery of their animal patients. In addition, irritation of the tissue in the form of an inserted stent can lead to overgrowth of granulation tissue, leading to the closure of the stent lumen, as is most often the case in the trachea. Such serious complications after stent placement require improvements in the procedures used to date. In this review, antibacterial or antibiofilm strategies for several stents used in veterinary medicine have been discussed based on the current literature and the perspectives have been drawn. Various coating strategies such as coating with hydrogel, antibiotic, or other antimicrobial agents have been reviewed. MDPI 2023-10-24 /pmc/articles/PMC10649059/ /pubmed/37959431 http://dx.doi.org/10.3390/ma16216834 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Graczyk, Szymon Pasławski, Robert Grzeczka, Arkadiusz Pasławska, Urszula Świeczko-Żurek, Beata Malisz, Klaudia Popat, Ketul Sionkowska, Alina Golińska, Patrycja Rai, Mahendra Antimicrobial and Antiproliferative Coatings for Stents in Veterinary Medicine—State of the Art and Perspectives |
title | Antimicrobial and Antiproliferative Coatings for Stents in Veterinary Medicine—State of the Art and Perspectives |
title_full | Antimicrobial and Antiproliferative Coatings for Stents in Veterinary Medicine—State of the Art and Perspectives |
title_fullStr | Antimicrobial and Antiproliferative Coatings for Stents in Veterinary Medicine—State of the Art and Perspectives |
title_full_unstemmed | Antimicrobial and Antiproliferative Coatings for Stents in Veterinary Medicine—State of the Art and Perspectives |
title_short | Antimicrobial and Antiproliferative Coatings for Stents in Veterinary Medicine—State of the Art and Perspectives |
title_sort | antimicrobial and antiproliferative coatings for stents in veterinary medicine—state of the art and perspectives |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649059/ https://www.ncbi.nlm.nih.gov/pubmed/37959431 http://dx.doi.org/10.3390/ma16216834 |
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