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Antimicrobial and Antiproliferative Coatings for Stents in Veterinary Medicine—State of the Art and Perspectives

Microbial colonization in veterinary stents poses a significant and concerning issue in veterinary medicine. Over time, these pathogens, particularly bacteria, can colonize the stent surfaces, leading to various complications. Two weeks following the stent insertion procedure, the colonization becom...

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Autores principales: Graczyk, Szymon, Pasławski, Robert, Grzeczka, Arkadiusz, Pasławska, Urszula, Świeczko-Żurek, Beata, Malisz, Klaudia, Popat, Ketul, Sionkowska, Alina, Golińska, Patrycja, Rai, Mahendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649059/
https://www.ncbi.nlm.nih.gov/pubmed/37959431
http://dx.doi.org/10.3390/ma16216834
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author Graczyk, Szymon
Pasławski, Robert
Grzeczka, Arkadiusz
Pasławska, Urszula
Świeczko-Żurek, Beata
Malisz, Klaudia
Popat, Ketul
Sionkowska, Alina
Golińska, Patrycja
Rai, Mahendra
author_facet Graczyk, Szymon
Pasławski, Robert
Grzeczka, Arkadiusz
Pasławska, Urszula
Świeczko-Żurek, Beata
Malisz, Klaudia
Popat, Ketul
Sionkowska, Alina
Golińska, Patrycja
Rai, Mahendra
author_sort Graczyk, Szymon
collection PubMed
description Microbial colonization in veterinary stents poses a significant and concerning issue in veterinary medicine. Over time, these pathogens, particularly bacteria, can colonize the stent surfaces, leading to various complications. Two weeks following the stent insertion procedure, the colonization becomes observable, with the aggressiveness of bacterial growth directly correlating with the duration of stent placement. Such microbial colonization can result in infections and inflammations, compromising the stent’s efficacy and, subsequently, the animal patient’s overall well-being. Managing and mitigating the impact of these pathogens on veterinary stents is a crucial challenge that veterinarians and researchers are actively addressing to ensure the successful treatment and recovery of their animal patients. In addition, irritation of the tissue in the form of an inserted stent can lead to overgrowth of granulation tissue, leading to the closure of the stent lumen, as is most often the case in the trachea. Such serious complications after stent placement require improvements in the procedures used to date. In this review, antibacterial or antibiofilm strategies for several stents used in veterinary medicine have been discussed based on the current literature and the perspectives have been drawn. Various coating strategies such as coating with hydrogel, antibiotic, or other antimicrobial agents have been reviewed.
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spelling pubmed-106490592023-10-24 Antimicrobial and Antiproliferative Coatings for Stents in Veterinary Medicine—State of the Art and Perspectives Graczyk, Szymon Pasławski, Robert Grzeczka, Arkadiusz Pasławska, Urszula Świeczko-Żurek, Beata Malisz, Klaudia Popat, Ketul Sionkowska, Alina Golińska, Patrycja Rai, Mahendra Materials (Basel) Review Microbial colonization in veterinary stents poses a significant and concerning issue in veterinary medicine. Over time, these pathogens, particularly bacteria, can colonize the stent surfaces, leading to various complications. Two weeks following the stent insertion procedure, the colonization becomes observable, with the aggressiveness of bacterial growth directly correlating with the duration of stent placement. Such microbial colonization can result in infections and inflammations, compromising the stent’s efficacy and, subsequently, the animal patient’s overall well-being. Managing and mitigating the impact of these pathogens on veterinary stents is a crucial challenge that veterinarians and researchers are actively addressing to ensure the successful treatment and recovery of their animal patients. In addition, irritation of the tissue in the form of an inserted stent can lead to overgrowth of granulation tissue, leading to the closure of the stent lumen, as is most often the case in the trachea. Such serious complications after stent placement require improvements in the procedures used to date. In this review, antibacterial or antibiofilm strategies for several stents used in veterinary medicine have been discussed based on the current literature and the perspectives have been drawn. Various coating strategies such as coating with hydrogel, antibiotic, or other antimicrobial agents have been reviewed. MDPI 2023-10-24 /pmc/articles/PMC10649059/ /pubmed/37959431 http://dx.doi.org/10.3390/ma16216834 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Graczyk, Szymon
Pasławski, Robert
Grzeczka, Arkadiusz
Pasławska, Urszula
Świeczko-Żurek, Beata
Malisz, Klaudia
Popat, Ketul
Sionkowska, Alina
Golińska, Patrycja
Rai, Mahendra
Antimicrobial and Antiproliferative Coatings for Stents in Veterinary Medicine—State of the Art and Perspectives
title Antimicrobial and Antiproliferative Coatings for Stents in Veterinary Medicine—State of the Art and Perspectives
title_full Antimicrobial and Antiproliferative Coatings for Stents in Veterinary Medicine—State of the Art and Perspectives
title_fullStr Antimicrobial and Antiproliferative Coatings for Stents in Veterinary Medicine—State of the Art and Perspectives
title_full_unstemmed Antimicrobial and Antiproliferative Coatings for Stents in Veterinary Medicine—State of the Art and Perspectives
title_short Antimicrobial and Antiproliferative Coatings for Stents in Veterinary Medicine—State of the Art and Perspectives
title_sort antimicrobial and antiproliferative coatings for stents in veterinary medicine—state of the art and perspectives
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649059/
https://www.ncbi.nlm.nih.gov/pubmed/37959431
http://dx.doi.org/10.3390/ma16216834
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