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Detrimental Effects of ApoE ε4 on Blood–Brain Barrier Integrity and Their Potential Implications on the Pathogenesis of Alzheimer’s Disease

Alzheimer’s disease (AD) is a progressive neurodegenerative disease representing the most common type of dementia in older adults. The major risk factors include increased age, genetic predisposition and socioeconomic factors. Among the genetic factors, the apolipoprotein E (ApoE) ε4 allele poses th...

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Detalles Bibliográficos
Autores principales:	Kirchner, Kevin, Garvert, Linda, Kühn, Luise, Bonk, Sarah, Grabe, Hans Jörgen, Van der Auwera, Sandra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Perspective
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649078/ https://www.ncbi.nlm.nih.gov/pubmed/37947590 http://dx.doi.org/10.3390/cells12212512

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