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Ethanol Extract of Rosa rugosa Ameliorates Acetaminophen-Induced Liver Injury via Upregulating Sirt1 and Subsequent Potentiation of LKB1/AMPK/Nrf2 Cascade in Hepatocytes

Acetaminophen (APAP)-induced liver injury is a common hepatic disease resulting from drug abuse. Few targeted treatments are available clinically nowadays. The flower bud of Rosa rugosa has a wide range of biological activities. However, it is unclear whether it alleviates liver injury caused by APA...

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Detalles Bibliográficos
Autores principales: Lei, Yecheng, Lei, Xiao, Zhu, Anqi, Xie, Shijie, Zhang, Tiantian, Wang, Chuo, Song, Anning, Wang, Xiaoming, Shu, Guangwen, Deng, Xukun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649261/
https://www.ncbi.nlm.nih.gov/pubmed/37959727
http://dx.doi.org/10.3390/molecules28217307