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The Neutrophil to Lymphocyte Ratio in Children with Bronchial Asthma

The discovery of an effective airway inflammation marker which correctly identifies the condition and phenotype of asthma still constitutes a significant challenge. The determination of NLR, that is, the ratio of neutrophils to lymphocytes, would overcome this challenge. The role of the neutrophil–l...

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Autores principales: Wawryk-Gawda, Ewelina, Żybowska, Monika, Ostrowicz, Klaudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649350/
https://www.ncbi.nlm.nih.gov/pubmed/37959334
http://dx.doi.org/10.3390/jcm12216869
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author Wawryk-Gawda, Ewelina
Żybowska, Monika
Ostrowicz, Klaudia
author_facet Wawryk-Gawda, Ewelina
Żybowska, Monika
Ostrowicz, Klaudia
author_sort Wawryk-Gawda, Ewelina
collection PubMed
description The discovery of an effective airway inflammation marker which correctly identifies the condition and phenotype of asthma still constitutes a significant challenge. The determination of NLR, that is, the ratio of neutrophils to lymphocytes, would overcome this challenge. The role of the neutrophil–lymphocytic index in the diagnosis of specific types of asthma is investigated in the present study. The results of laboratory tests of 482 pediatric patients were used for the analysis. The results of 107 children without allergic disease symptoms were selected for the control group. The mean NLR in patients with asthma was 3.42 ± 4.05, and in the control group it was 1.94 ± 1.91. The difference between the NLR in allergic and non-allergic asthma was statistically significant in the allergic asthma and control groups. There was no statistically significant difference between NLR and body temperature, BMI, and gender. The value of NLR was significantly higher in the blood of patients suffering from asthma compared to the control group. The NLR was the highest among patients with allergic asthma. The use of this blood test in daily practice may facilitate the diagnosis of asthma and differentiation between asthma types, especially when the results of other tests are inconclusive.
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spelling pubmed-106493502023-10-31 The Neutrophil to Lymphocyte Ratio in Children with Bronchial Asthma Wawryk-Gawda, Ewelina Żybowska, Monika Ostrowicz, Klaudia J Clin Med Article The discovery of an effective airway inflammation marker which correctly identifies the condition and phenotype of asthma still constitutes a significant challenge. The determination of NLR, that is, the ratio of neutrophils to lymphocytes, would overcome this challenge. The role of the neutrophil–lymphocytic index in the diagnosis of specific types of asthma is investigated in the present study. The results of laboratory tests of 482 pediatric patients were used for the analysis. The results of 107 children without allergic disease symptoms were selected for the control group. The mean NLR in patients with asthma was 3.42 ± 4.05, and in the control group it was 1.94 ± 1.91. The difference between the NLR in allergic and non-allergic asthma was statistically significant in the allergic asthma and control groups. There was no statistically significant difference between NLR and body temperature, BMI, and gender. The value of NLR was significantly higher in the blood of patients suffering from asthma compared to the control group. The NLR was the highest among patients with allergic asthma. The use of this blood test in daily practice may facilitate the diagnosis of asthma and differentiation between asthma types, especially when the results of other tests are inconclusive. MDPI 2023-10-31 /pmc/articles/PMC10649350/ /pubmed/37959334 http://dx.doi.org/10.3390/jcm12216869 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Wawryk-Gawda, Ewelina
Żybowska, Monika
Ostrowicz, Klaudia
The Neutrophil to Lymphocyte Ratio in Children with Bronchial Asthma
title The Neutrophil to Lymphocyte Ratio in Children with Bronchial Asthma
title_full The Neutrophil to Lymphocyte Ratio in Children with Bronchial Asthma
title_fullStr The Neutrophil to Lymphocyte Ratio in Children with Bronchial Asthma
title_full_unstemmed The Neutrophil to Lymphocyte Ratio in Children with Bronchial Asthma
title_short The Neutrophil to Lymphocyte Ratio in Children with Bronchial Asthma
title_sort neutrophil to lymphocyte ratio in children with bronchial asthma
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649350/
https://www.ncbi.nlm.nih.gov/pubmed/37959334
http://dx.doi.org/10.3390/jcm12216869
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