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The Neutrophil to Lymphocyte Ratio in Children with Bronchial Asthma
The discovery of an effective airway inflammation marker which correctly identifies the condition and phenotype of asthma still constitutes a significant challenge. The determination of NLR, that is, the ratio of neutrophils to lymphocytes, would overcome this challenge. The role of the neutrophil–l...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649350/ https://www.ncbi.nlm.nih.gov/pubmed/37959334 http://dx.doi.org/10.3390/jcm12216869 |
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author | Wawryk-Gawda, Ewelina Żybowska, Monika Ostrowicz, Klaudia |
author_facet | Wawryk-Gawda, Ewelina Żybowska, Monika Ostrowicz, Klaudia |
author_sort | Wawryk-Gawda, Ewelina |
collection | PubMed |
description | The discovery of an effective airway inflammation marker which correctly identifies the condition and phenotype of asthma still constitutes a significant challenge. The determination of NLR, that is, the ratio of neutrophils to lymphocytes, would overcome this challenge. The role of the neutrophil–lymphocytic index in the diagnosis of specific types of asthma is investigated in the present study. The results of laboratory tests of 482 pediatric patients were used for the analysis. The results of 107 children without allergic disease symptoms were selected for the control group. The mean NLR in patients with asthma was 3.42 ± 4.05, and in the control group it was 1.94 ± 1.91. The difference between the NLR in allergic and non-allergic asthma was statistically significant in the allergic asthma and control groups. There was no statistically significant difference between NLR and body temperature, BMI, and gender. The value of NLR was significantly higher in the blood of patients suffering from asthma compared to the control group. The NLR was the highest among patients with allergic asthma. The use of this blood test in daily practice may facilitate the diagnosis of asthma and differentiation between asthma types, especially when the results of other tests are inconclusive. |
format | Online Article Text |
id | pubmed-10649350 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-106493502023-10-31 The Neutrophil to Lymphocyte Ratio in Children with Bronchial Asthma Wawryk-Gawda, Ewelina Żybowska, Monika Ostrowicz, Klaudia J Clin Med Article The discovery of an effective airway inflammation marker which correctly identifies the condition and phenotype of asthma still constitutes a significant challenge. The determination of NLR, that is, the ratio of neutrophils to lymphocytes, would overcome this challenge. The role of the neutrophil–lymphocytic index in the diagnosis of specific types of asthma is investigated in the present study. The results of laboratory tests of 482 pediatric patients were used for the analysis. The results of 107 children without allergic disease symptoms were selected for the control group. The mean NLR in patients with asthma was 3.42 ± 4.05, and in the control group it was 1.94 ± 1.91. The difference between the NLR in allergic and non-allergic asthma was statistically significant in the allergic asthma and control groups. There was no statistically significant difference between NLR and body temperature, BMI, and gender. The value of NLR was significantly higher in the blood of patients suffering from asthma compared to the control group. The NLR was the highest among patients with allergic asthma. The use of this blood test in daily practice may facilitate the diagnosis of asthma and differentiation between asthma types, especially when the results of other tests are inconclusive. MDPI 2023-10-31 /pmc/articles/PMC10649350/ /pubmed/37959334 http://dx.doi.org/10.3390/jcm12216869 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Wawryk-Gawda, Ewelina Żybowska, Monika Ostrowicz, Klaudia The Neutrophil to Lymphocyte Ratio in Children with Bronchial Asthma |
title | The Neutrophil to Lymphocyte Ratio in Children with Bronchial Asthma |
title_full | The Neutrophil to Lymphocyte Ratio in Children with Bronchial Asthma |
title_fullStr | The Neutrophil to Lymphocyte Ratio in Children with Bronchial Asthma |
title_full_unstemmed | The Neutrophil to Lymphocyte Ratio in Children with Bronchial Asthma |
title_short | The Neutrophil to Lymphocyte Ratio in Children with Bronchial Asthma |
title_sort | neutrophil to lymphocyte ratio in children with bronchial asthma |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649350/ https://www.ncbi.nlm.nih.gov/pubmed/37959334 http://dx.doi.org/10.3390/jcm12216869 |
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