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Stimulation of the Pro-Resolving Receptor Fpr2 Reverses Inflammatory Microglial Activity by Suppressing NFκB Activity

Neuroinflammation driven primarily by microglia directly contributes to neuronal death in many neurodegenerative diseases. Classical anti-inflammatory approaches aim to suppress pro-inflammatory mediator production, but exploitation of inflammatory resolution may also be of benefit. A key driver of...

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Detalles Bibliográficos
Autores principales: Wickstead, Edward S., Elliott, Bradley T., Pokorny, Sarah, Biggs, Christopher, Getting, Stephen J., McArthur, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649357/
https://www.ncbi.nlm.nih.gov/pubmed/37958978
http://dx.doi.org/10.3390/ijms242115996