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Stimulation of the Pro-Resolving Receptor Fpr2 Reverses Inflammatory Microglial Activity by Suppressing NFκB Activity
Neuroinflammation driven primarily by microglia directly contributes to neuronal death in many neurodegenerative diseases. Classical anti-inflammatory approaches aim to suppress pro-inflammatory mediator production, but exploitation of inflammatory resolution may also be of benefit. A key driver of...
Autores principales: | Wickstead, Edward S., Elliott, Bradley T., Pokorny, Sarah, Biggs, Christopher, Getting, Stephen J., McArthur, Simon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649357/ https://www.ncbi.nlm.nih.gov/pubmed/37958978 http://dx.doi.org/10.3390/ijms242115996 |
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