The Small GTPase Rab7 Regulates Antigen Processing in B Cells in a Possible Interplay with Autophagy Machinery

In B cells, antigen processing and peptide-antigen (pAg) presentation is essential to ignite high-affinity antibody responses with the help of cognate T cells. B cells efficiently internalize and direct specific antigens for processing and loading onto MHCII. This critical step, which enables pAg pr...

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Detalles Bibliográficos
Autores principales: Runsala, Marika, Kuokkanen, Elina, Uski, Eveliina, Šuštar, Vid, Balci, Meryem Özge, Rajala, Johanna, Paavola, Vilma, Mattila, Pieta K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649364/
https://www.ncbi.nlm.nih.gov/pubmed/37947644
http://dx.doi.org/10.3390/cells12212566

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