Five Inhibitory Receptors Display Distinct Vesicular Distributions in Murine T Cells

T cells can express multiple inhibitory receptors. Upon induction of T cell exhaustion in response to a persistent antigen, prominently in the anti-tumor immune response, many are expressed simultaneously. Key inhibitory receptors are CTLA-4, PD-1, LAG3, TIM3, and TIGIT, as investigated here. These...

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Detalles Bibliográficos
Autores principales: Lu, Jiahe, Veler, Alisa, Simonetti, Boris, Raj, Timsse, Chou, Po Han, Cross, Stephen J., Phillips, Alexander M., Ruan, Xiongtao, Huynh, Lan, Dowsey, Andrew W., Ye, Dingwei, Murphy, Robert F., Verkade, Paul, Cullen, Peter J., Wülfing, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649679/
https://www.ncbi.nlm.nih.gov/pubmed/37947636
http://dx.doi.org/10.3390/cells12212558

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