BRAF Inhibitors in Metastatic Colorectal Cancer and Mechanisms of Resistance: A Review of the Literature

SIMPLE SUMMARY: The MAP kinases pathway has shown a key role in the pathogenesis of colorectal cancer. The development of targeted therapy against BRAF-mutated tumors is changing the management of advanced disease. A proper understanding of the mechanisms of acquired resistance is essential to optim...

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Detalles Bibliográficos
Autores principales: Guerrero, Patricia, Albarrán, Víctor, San Román, María, González-Merino, Carlos, García de Quevedo, Coral, Moreno, Jaime, Calvo, Juan Carlos, González, Guillermo, Orejana, Inmaculada, Chamorro, Jesús, Martínez-Delfrade, Íñigo, Morón, Blanca, de Frutos, Belén, Ferreiro, María Reyes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649848/
https://www.ncbi.nlm.nih.gov/pubmed/37958416
http://dx.doi.org/10.3390/cancers15215243

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