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Tumor cell-induced macrophage senescence plays a pivotal role in tumor initiation followed by stable growth in immunocompetent condition

BACKGROUND: The cancer stem cell theory proposes that tumor formation in vivo is driven only by specific tumor-initiating cells having stemness; however, clinical trials conducted to test drugs that target the tumor stemness provided unsatisfactory results thus far. Recent studies showed clear invol...

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Detalles Bibliográficos
Autores principales:	Wada, Haruka, Otsuka, Ryo, Germeraad, Wilfred T V, Murata, Tomoki, Kondo, Toru, Seino, Ken-ichiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2023
Materias:	Basic Tumor Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649871/ https://www.ncbi.nlm.nih.gov/pubmed/37963635 http://dx.doi.org/10.1136/jitc-2023-006677

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