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The Link between Periodontal Disease and Asthma: How Do These Two Diseases Affect Each Other?

A growing body of evidence suggests that the effects of poor oral hygiene extend beyond the oral cavity and are associated with a variety of systemic diseases, including asthma. Asthma, which results in symptoms of cough, wheezing, and dyspnoea, and is characterized by airflow limitation with variab...

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Autores principales: Tamiya, Hiroyuki, Abe, Masanobu, Nagase, Takahide, Mitani, Akihisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10650117/
https://www.ncbi.nlm.nih.gov/pubmed/37959214
http://dx.doi.org/10.3390/jcm12216747
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author Tamiya, Hiroyuki
Abe, Masanobu
Nagase, Takahide
Mitani, Akihisa
author_facet Tamiya, Hiroyuki
Abe, Masanobu
Nagase, Takahide
Mitani, Akihisa
author_sort Tamiya, Hiroyuki
collection PubMed
description A growing body of evidence suggests that the effects of poor oral hygiene extend beyond the oral cavity and are associated with a variety of systemic diseases, including asthma. Asthma, which results in symptoms of cough, wheezing, and dyspnoea, and is characterized by airflow limitation with variability and (partial or complete) reversibility, is amongst the most prevalent respiratory diseases with approximately 262 million patients worldwide, and its prevalence and disease burden is on the increase. While asthma can occur at a young age, it can also develop later in life and affects a variety of age groups. Both of these diseases have a chronic course, and various researchers have suggested a link between the two. In this article, we aim to provide a literature review focusing on the association between the two diseases. The results demonstrate that medications (primarily, inhaler medicine), hypoxia induced by asthma, and the breathing behaviour of patients potentially trigger periodontal disease. In contrast, oral periodontopathogenic microorganisms and the inflammatory mediators produced by them may be involved in the onset and/or exacerbation of asthma. Common contributing factors, such as smoking, gastro-oesophageal reflux, and type-2 inflammation, should also be considered when evaluating the relationship between the two diseases.
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spelling pubmed-106501172023-10-25 The Link between Periodontal Disease and Asthma: How Do These Two Diseases Affect Each Other? Tamiya, Hiroyuki Abe, Masanobu Nagase, Takahide Mitani, Akihisa J Clin Med Review A growing body of evidence suggests that the effects of poor oral hygiene extend beyond the oral cavity and are associated with a variety of systemic diseases, including asthma. Asthma, which results in symptoms of cough, wheezing, and dyspnoea, and is characterized by airflow limitation with variability and (partial or complete) reversibility, is amongst the most prevalent respiratory diseases with approximately 262 million patients worldwide, and its prevalence and disease burden is on the increase. While asthma can occur at a young age, it can also develop later in life and affects a variety of age groups. Both of these diseases have a chronic course, and various researchers have suggested a link between the two. In this article, we aim to provide a literature review focusing on the association between the two diseases. The results demonstrate that medications (primarily, inhaler medicine), hypoxia induced by asthma, and the breathing behaviour of patients potentially trigger periodontal disease. In contrast, oral periodontopathogenic microorganisms and the inflammatory mediators produced by them may be involved in the onset and/or exacerbation of asthma. Common contributing factors, such as smoking, gastro-oesophageal reflux, and type-2 inflammation, should also be considered when evaluating the relationship between the two diseases. MDPI 2023-10-25 /pmc/articles/PMC10650117/ /pubmed/37959214 http://dx.doi.org/10.3390/jcm12216747 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Tamiya, Hiroyuki
Abe, Masanobu
Nagase, Takahide
Mitani, Akihisa
The Link between Periodontal Disease and Asthma: How Do These Two Diseases Affect Each Other?
title The Link between Periodontal Disease and Asthma: How Do These Two Diseases Affect Each Other?
title_full The Link between Periodontal Disease and Asthma: How Do These Two Diseases Affect Each Other?
title_fullStr The Link between Periodontal Disease and Asthma: How Do These Two Diseases Affect Each Other?
title_full_unstemmed The Link between Periodontal Disease and Asthma: How Do These Two Diseases Affect Each Other?
title_short The Link between Periodontal Disease and Asthma: How Do These Two Diseases Affect Each Other?
title_sort link between periodontal disease and asthma: how do these two diseases affect each other?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10650117/
https://www.ncbi.nlm.nih.gov/pubmed/37959214
http://dx.doi.org/10.3390/jcm12216747
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