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Investigating the Effects of Exogenous and Endogenous 2-Arachidonoylglycerol on Retinal CB1 Cannabinoid Receptors and Reactive Microglia in Naive and Diseased Retina

The endocannabinoid system (ECS) is a new target for the development of retinal disease therapeutics, whose pathophysiology involves neurodegeneration and neuroinflammation. The endocannabinoid 2-arachidonoylglycerol (2-AG) affects neurons and microglia by activating CB1/CB2 cannabinoid receptors (R...

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Detalles Bibliográficos
Autores principales: Papadogkonaki, Sofia, Spyridakos, Dimitris, Lapokonstantaki, Emmanouela, Chaniotakis, Nikos, Makriyannis, Alexandros, Malamas, Michael S., Thermos, Kyriaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10650178/
https://www.ncbi.nlm.nih.gov/pubmed/37958673
http://dx.doi.org/10.3390/ijms242115689