Tyrosine Metabolism Pathway Is Downregulated in Dopaminergic Neurons with LRRK2 Overexpression in Drosophila

LRRK2 mutations are the leading cause of familial Parkinson’s disease (PD) and are a significant risk factor for idiopathic PD cases. However, the molecular mechanisms underlying the degeneration of dopaminergic (DA) neurons in LRRK2 PD patients remain unclear. To determine the translatomic impact o...

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Detalles Bibliográficos
Autores principales: Cheng, Jack, Wu, Bor-Tsang, Liu, Hsin-Ping, Lin, Wei-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10650192/
https://www.ncbi.nlm.nih.gov/pubmed/37958569
http://dx.doi.org/10.3390/ijms242115587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10650192/
https://www.ncbi.nlm.nih.gov/pubmed/37958569
http://dx.doi.org/10.3390/ijms242115587

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