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GRF2 Is Crucial for Cone Photoreceptor Viability and Ribbon Synapse Formation in the Mouse Retina
Using constitutive GRF1/2 knockout mice, we showed previously that GRF2 is a key regulator of nuclear migration in retinal cone photoreceptors. To evaluate the functional relevance of that cellular process for two putative targets of the GEF activity of GRF2 (RAC1 and CDC42), here we compared the st...
Autores principales: | Jimeno, David, Lillo, Concepción, de la Villa, Pedro, Calzada, Nuria, Santos, Eugenio, Fernández-Medarde, Alberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10650203/ https://www.ncbi.nlm.nih.gov/pubmed/37947653 http://dx.doi.org/10.3390/cells12212574 |
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