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GRF2 Is Crucial for Cone Photoreceptor Viability and Ribbon Synapse Formation in the Mouse Retina

Using constitutive GRF1/2 knockout mice, we showed previously that GRF2 is a key regulator of nuclear migration in retinal cone photoreceptors. To evaluate the functional relevance of that cellular process for two putative targets of the GEF activity of GRF2 (RAC1 and CDC42), here we compared the st...

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Detalles Bibliográficos
Autores principales: Jimeno, David, Lillo, Concepción, de la Villa, Pedro, Calzada, Nuria, Santos, Eugenio, Fernández-Medarde, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10650203/
https://www.ncbi.nlm.nih.gov/pubmed/37947653
http://dx.doi.org/10.3390/cells12212574

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